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Expression data from human primary fibroblasts, endothelial and smooth muscle cells infected with Trypanosoma cruzi

(Submitter supplied) Trypanosoma cruzi is an obligate intracellular protozoan parasite that causes human Chagas’ disease, a leading cause of heart failure in Latin America. Using Affymetrix oligonucleotide arrays we screened phenotypically diverse human cells (foreskin fibroblasts, microvascular endothelial cells and vascular smooth muscle cells) for a common transcriptional response signature to T. cruzi. A common feature was a prominent type I interferon response, indicative of a secondary response to secreted cytokines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
26 Samples
Download data: CEL
Series
Accession:
GSE13791
ID:
200013791

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