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Items: 3

1.

PGA Rat Liver Methylprednisolone

(Submitter supplied) Summary: The liver is the major site of gluconeogenesis, fat processing and distribution, as well as drug and xenobiotic metabolism. Altered gene expression in the liver is centrally invovled in both the immuosuppressive and the energetic actions of corticosteroids. Hypothesis: That pharmacodynamics can be derived from expression profiling data. Specific Aim: The aim of this project is to identify distinct temporal patters of RNA expression in the liver of rats following a bolus dose of the corticosteroid methylprednisolone. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Datasets:
GDS253 GDS972
Platforms:
GPL341 GPL85
91 Samples
Download data: CEL
Series
Accession:
GSE487
ID:
200000487

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.
Full record GDS972

Methylprednisolone effect on liver: time course (RAE230A)

Expression profiling of liver from animals treated with methylprednisolone. Liver examined at various time points up to 168 hours following methylprednisolone treatment. Results provide insight into prednisone pharmacodynamics.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 11 time sets
Platform:
GPL341
Series:
GSE487
44 Samples
Download data: CEL
DataSet
Accession:
GDS972
ID:
972

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

3.
Full record GDS253

Methylprednisolone effect on liver: time course

Expression profiling of liver from animals treated with methylprednisolone. Liver examined at various time points up to 72 hours following methylprednisolone treatment. Results provide insight into prednisone pharmacodynamics.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 17 time sets
Platform:
GPL85
Series:
GSE487
46 Samples
Download data: CEL
DataSet
Accession:
GDS253
ID:
253

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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