GEO DataSet Links for PMC (Select 3341041) - GEO DataSets

Select item 2000197661.

Transcriptional responses of mouse bone marrow-derived macrophages (BMM) to lipopolysaccharide (LPS) - Illumina arrays

(Submitter supplied) These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in mouse macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19490 for custom array analysis).

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4055
11 Samples

Download data: TXT

Series

Accession:: GSE19766

ID:: 200019766

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000197652.

Transcriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) - Illumina arrays

(Submitter supplied) These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in human monocyte-derived macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19482 for custom array analysis).

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6102
10 Samples

Download data: TXT

Series

Accession:: GSE19765

ID:: 200019765

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000194923.

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by array

4 related Platforms
61 Samples

Download data: TXT

Series

Accession:: GSE19492

ID:: 200019492

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000194904.

Transcriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS)

(Submitter supplied) Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agonist, LPS. Using a custom platform permitting cross-species interrogation coupled with deep sequencing of mRNA 5’ ends, we identified extensive divergence in LPS-regulated orthologous gene expression between humans and mice (24% of orthologs, http://www.macgate.qfab.org). more...