GEO DataSet Links for PMC (Select 3372375) - GEO DataSets

Select item 2000340371.

Genome-wide distribution of AdpA, a global regulator for secondary metabolism and morphological differentiation in Streptomyces [solid]

(Submitter supplied) AdpA is a global transcriptional activator triggering morphological differentiation and secondary metabolism in Streptomyces griseus. AdpA influences expression of >1,000 genes, but the overall picture of AdpA regulon has been obscure. Here, we took snapshots of distribution of AdpA across the chromosome in living S. griseus cells by ChIP/ChAP-seq analysis. In both liquid and solid cultures, AdpA bound to similar >1,200 sites, which were located on not only putative regulatory regions (65 %) but also regions (35 %) that appeared not to affect transcription. more...

Organism:: Streptomyces griseus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL14940
3 Samples

Download data: SAM

Series

Accession:: GSE34037

ID:: 200034037

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000340362.

Genome-wide distribution of AdpA, a global regulator for secondary metabolism and morphological differentiation in Streptomyces [liquid]

(Submitter supplied) AdpA is a global transcriptional activator triggering morphological differentiation and secondary metabolism in Streptomyces griseus. AdpA influences expression of >1,000 genes, but the overall picture of AdpA regulon has been obscure. Here, we took snapshots of distribution of AdpA across the chromosome in living S. griseus cells by ChIP/ChAP-seq analysis. In both liquid and solid cultures, AdpA bound to similar >1,200 sites, which were located on not only putative regulatory regions (65 %) but also regions (35 %) that appeared not to affect transcription. more...

Organism:: Streptomyces griseus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL14940
2 Samples

Download data: TXT

Series

Accession:: GSE34036

ID:: 200034036

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000339943.

Genome-wide distribution of AdpA, a global regulator for secondary metabolism and morphological differentiation in Streptomyces, revealed the extent and complexity of the AdpA regulatory network.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Streptomyces griseus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL5473 GPL14940
9 Samples

Download data: SAM, TXT

Series

Accession:: GSE33994

ID:: 200033994

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000339934.

Streptomyces griseus transcriptome analysis in liquid culture with delta adpA, encoding a global transcriptional regulator involved in morphological differentiation and secondary metabolism

(Submitter supplied) To identify genes regulated by AdpA in liquid culture, transcriptome profiles between delta adpA strains with his-adpA and control delta adpA strains were analyzed.

Organism:: Streptomyces griseus

Type:: Expression profiling by array

Platform:: GPL5473
1 Sample

Download data: TXT

Series

Accession:: GSE33993

ID:: 200033993

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000339925.

Streptomyces griseus transcriptome analysis in solid culture with delta adpA, encoding a global transcriptional regulator involved in morphological differentiation and secondary metabolism

(Submitter supplied) To identify genes regulated by AdpA in solid culture, transcriptome profiles between delta adpA strains with his-adpA and control delta adpA strains were analyzed.

Organism:: Streptomyces griseus

Type:: Expression profiling by array

Platform:: GPL5473
3 Samples

Download data: TXT

Series

Accession:: GSE33992

ID:: 200033992

PubMed Full text in PMC Similar studies Analyze with GEO2R

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