GEO DataSet Links for PMC (Select 3581146) - GEO DataSets

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Items: 2

Select item 2000290841.

Expression Data from HNF4a RNAi Knockdown in HepG2 cells

(Submitter supplied) HNF4a is an important liver transcription factor that regulates at least a thousand genes in the liver. Here we used expression profiling in HepG2 cells, a hepatocellular carcinoma cell line, in which HNF4a was knocked down by RNAi to identify some of those target genes. This dataset accompanies the article in Hepatology 2010 Feb;51(2):642-53. Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays by Bolotin E, Liao H, Ta TC, Yang C, Hwang-Verslues W, Evans JR, Jiang T, Sladek FM.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4798
Platform:: GPL570
4 Samples

Download data: CEL

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Accession:: GSE29084

ID:: 200029084

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 47982.

Hepatocyte nuclear factor 4 alpha depletion effect on hepatocellular carcinoma cell line

Analysis of HepG2 hepatocellular carcinoma cells depleted for HNF4alpha, a member of the nuclear receptor superfamily. HNF4alpha is essential for liver function and is linked to several diseases such as diabetes and hepatitis. Results provide insight into identification of HNF4alpha target genes.