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Rapid and Pervasive Changes in Genome-Wide Enhancer Usage During Mammalian Development

(Submitter supplied) Here we used epigenomic profiling for H3K27ac, a mark of active enhancers to examine the genome-wide in vivo utilization of enhancers in three different mouse tissues across seven developmental stages, ranging from mid-gestation through adulthood. The majority of the ~90,000 enhancers identified exhibited tightly temporally restricted activity windows and were associated with stage-specific biological functions and regulatory pathways in individual tissues. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
48 Samples
Download data: BED, WIG, XLSX
Series
Accession:
GSE52386
ID:
200052386

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