GEO DataSets

(Submitter supplied) We have shown that worms that possess mutations in two electron transport chain subunits live longer due to mtROS signalling. Wild type worms can also live longer by treatment with the pro-oxidant paraquat. Paraquat treatment is not additive to the mutations in the ETC subunits. We aimed to determine the underlying changes in gene expression that were common to both paraquat treatment and the two mutations. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

Datasets:

GDS5193 GDS5194 GDS5195

Platform:

GPL200

22 Samples

Download data: CEL

Analysis of nuo-6;ced-4 double mutants. ced-4 mutation in the intrinsic apoptosis signaling pathway suppresses the longevity of electron transport chain mutant nuo-6. Results provide insight into molecular mechanisms underlying lifespan expansion.

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array, transformed count, 4 genotype/variation sets

Platform:

GPL200

Series:

GSE54024

13 Samples

Download data: CEL

Analysis of isp-1;ced-4 double mutants. ced-4 mutation in the intrinsic apoptosis signaling pathway suppresses the longevity of electron transport chain mutant isp-1. Results provide insight into molecular mechanisms underlying lifespan expansion.

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array, transformed count, 4 genotype/variation sets

Platform:

GPL200

Series:

GSE54024

13 Samples

Download data: CEL

Analysis of wildtype worms treated with the pro-oxidant paraquat and electron transport chain mutants isp-1 and nuo-6. Results provide insight into common molecular mechanisms underlying the increased longevity in all three conditions.

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array, transformed count, 3 genotype/variation, 3 protocol sets

Platform:

GPL200

Series:

GSE54024

13 Samples

Download data: CEL