The CBF1/L3MBTL3 axis promotes the repression of Notch signaling by the histone demethylase KDM1A - - GEO DataSets

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The CBF1/L3MBTL3 axis promotes the repression of Notch signaling by the histone demethylase KDM1A

(Submitter supplied) We performed ChIP-seq experiments to investigate on a genome-wide scale the co-localization of CBF1 (also known as RBPJ or CSL) and L3MBTL3 on chromatin in the MDA-MB-231 cell line. Analysis of the CBF1 and L3MBTL3 ChIP-seq experiments in the MDA-MB-231 cell line revealed a substantial and significant genome-wide co-localization on chromatin, in agreement with our hypothesis that CBF1 contributes to the recruitment of L3MBTL3 to chromatin.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
3 Samples

Download data: BIGWIG, TXT

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Accession:: GSE100375

ID:: 200100375

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