GEO DataSet Links for PMC (Select 5785461) - GEO DataSets

Select item 2000894181.

EZH1 as a key epigenetic barrier to definitive haematopoiesis during embryonic development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms
58 Samples

Download data: BED, TXT, WIG

Series

Accession:: GSE89418

ID:: 200089418

PubMed Full text in PMC Similar studies

Select item 2000894172.

ChIP-seq analysis of EZH1, H3K4me3 and H3K27me3 in 5F cells

(Submitter supplied) Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted differentiation potential relative to definitive haematopoietic stem cells in adult bone marrow, which support lifelong multilineage haematopoiesis. To identify regulators of embryonic haematopoiesis, we screened chromatin modifiers and identified the Polycomb group protein EZH1 as a barrier to multilineage potential from pluripotent stem cells (PSCs). more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
15 Samples

Download data: BED, WIG

Series

Accession:: GSE89417

ID:: 200089417

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000894163.

ATAC-seq analysis in 5F cells and AGM cells with EZH1 depletion

(Submitter supplied) Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted differentiation potential relative to definitive haematopoietic stem cells in adult bone marrow, which support lifelong multilineage haematopoiesis. To identify regulators of embryonic haematopoiesis, we screened chromatin modifiers and identified the Polycomb group protein EZH1 as a barrier to multilineage potential from pluripotent stem cells (PSCs). more...

Organism:: Homo sapiens; Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL19057 GPL18573
7 Samples

Download data: BED, WIG

Series

Accession:: GSE89416

ID:: 200089416

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000894154.

RNA-seq analysis of EZH1 knockdown in 5F cells, or EZH1 heterozygous and homozygous knockout YS and AGM cells

(Submitter supplied) Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted differentiation potential relative to definitive haematopoietic stem cells in adult bone marrow, which support lifelong multilineage haematopoiesis. To identify regulators of embryonic haematopoiesis, we screened chromatin modifiers and identified the Polycomb group protein EZH1 as a barrier to multilineage potential from pluripotent stem cells (PSCs). more...

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL17021 GPL16791
36 Samples

Download data: TXT

Series

Accession:: GSE89415

ID:: 200089415

PubMed Full text in PMC Similar studies SRA Run Selector

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