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DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

(Submitter supplied) Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm), underlie the relationship between adverse intrauterine conditions and adult metabolic health, evidence from human studies remains scarce. Therefore, we evaluated whether DNAm in whole blood mediated the association between prenatal famine exposure and metabolic health in 422 individuals exposed to famine in utero and 463 (sibling) controls. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
152 Samples
Download data: TXT
Series
Accession:
GSE78743
ID:
200078743

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