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Lung endothelial cells (MLECs) from knock-in mouse model with or without the causative HGPS LmnaG609G mutation

(Submitter supplied) Vascular dysfunction is one of the typical characteristics of aging, but its contributing roles to systemic aging and the therapeutic potential is lacking experimental evidence. Accumulating data suggest that the mechanisms underlying aging are similar to those governing Hutchinson-Gilford progeria syndrome (HGPS), a premature aging disease, in which affected patients succumb to cardiovascular diseases (CVDs). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
2 Samples
Download data: CLOUPE
Series
Accession:
GSE138975
ID:
200138975

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