SUM159 cells grown in 2D cultures in the presence or absence of SHP2 - - GEO DataSets

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SUM159 cells grown in 2D cultures in the presence or absence of SHP2

(Submitter supplied) The first bona fide PTP proto-oncogene was the Src-homology 2 domain-containing phosphatase SHP2 (encoded by PTPN11), an ubiquitously expressed PTP that transduces mitogenic, pro-survival, cell fate and/or pro-migratory signals from numerous growth factor-, cytokine- and extracellular matrix receptors. In malignancies, SHP2 is hyperactivated either downstream of oncoproteins or by mutations.We provide analysis of the human mesenchymal triple-negative breast cancer cell line SUM159 and grown in 2D cultures for 15 days in the presence or absence of SHP2.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
7 Samples

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Accession:: GSE182033

ID:: 200182033

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