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Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification. [RNA-Seq]

(Submitter supplied) Purpose: A systematic analysis of the transcriptomic profile of HGPS patient-derived fibroblasts, stratifying the analysis by comparing defined age groups to matched controls Methods: Total mRNA, acquired from Coriell Institute for Medical Research was submitted for RNA-seq library preparation and sequencing at Genewiz. Libraries were prepared using Illumina, RNA with PolyA selection approach, and then sequenced on a HiSeq instrument using 2x150 bp sequencing. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
11 Samples
Download data: TSV
Series
Accession:
GSE206684
ID:
200206684

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