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Items: 2

1.

LAPC4_R1881_DMSO_22h_rep6

Organism:
Homo sapiens
Source name:
LAPC-4 (prostate)
Platform:
GPL16791
Series:
GSE148397 GSE148400
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Sample
Accession:
GSM4467254
ID:
304467254
2.

Darolutamide antagonizes androgen signaling by blocking enhancer and super-enhancer activation [RNA-seq]

(Submitter supplied) The androgen receptor (AR) antagonist darolutamide has very recently been approved for the treatment of non-metastatic castration resistant prostate cancer (PCa). Here we determined the genome-wide effects of darolutamide on cis-acting regulatory elements involved in androgen signaling with a focus on enhancer and super-enhancer (SE) regions. Darolutamide strongly depleted the AR from regulatory elements and abolished the AR transcriptional signaling. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
112 Samples
Download data: TSV

Supplemental Content

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