GEO DataSet Links for SRA (Select 32468497) - GEO DataSets

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Items: 2

Select item 3081881621.

GlambdaL, st14, rep2

Organism:: Drosophila melanogaster

Source name:: whole embryo, st14

Platform:: GPL25244
Series:: GSE263229

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Accession:: GSM8188162

ID:: 308188162

SRA Run Selector

Select item 2002632292.

Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion

(Submitter supplied) Two different models have been proposed to explain how the endpoints of chromatin looped domains (“TADs”) in eukaryotic chromosomes are determined. In the first, a cohesin complex extrudes a loop until it encounters a boundary element roadblock, generating a stem-loop (and an unanchored loop). In this model, boundaries are functionally autonomous: they have an intrinsic ability to halt the movement of incoming cohesin complexes that is independent of the properties of neighboring boundaries. more...