GEO DataSet Links for SRA (Select 3902033) - GEO DataSets

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Items: 2

Select item 3025634641.

A3: High Fat-Early Exercise (HF-EEX)

Organism:: Rattus norvegicus

Source name:: Femoral mid-diaphysis marrow

Platform:: GPL22396
Series:: GSE97376

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Accession:: GSM2563464

ID:: 302563464

SRA Run Selector

Select item 2000973762.

A memory of early life physical activity is retained in bone marrow of adult rats but does not prevent reversal to obese phenotype

(Submitter supplied) Studies have reported opposing effects of high-fat diet and mechanical stimulation on lineage commitment of the bone marrow stem cells. Yet, how the bone marrow modulates its gene expression in response to the combined effects of mechanical loading and a high-fat diet has not yet been addressed. We investigated whether early-life voluntary physical activity can modulate the effects of a high-fat diet on body composition, bone phenotype and bone marrow gene expression in male Sprague Dawley rats. more...