GEO DataSet Links for SRA (Select 4467873) - GEO DataSets

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Items: 2

Select item 3027747991.

RNAseq_non_dysgenic_rep2

Organism:: Drosophila melanogaster

Source name:: non_dysgenic

Platform:: GPL17275
Series:: GSE103582

Download data: BIGWIG

Sample

Accession:: GSM2774799

ID:: 302774799

SRA Run Selector

Select item 2001035822.

piRNA-mediated regulation of transposon alternative splicing in soma and germline

(Submitter supplied) Transposable elements can drive genome evolution, but their enhanced activity is detrimental to the host and therefore must be tightly regulated. The piwi-interacting small RNAs (piRNAs) pathway is critically important for transposable element regulation, by inducing transcriptional silencing or post-transcriptional decay of mRNAs. We show that piRNAs and piRNA biogenesis components regulate pre-mRNA splicing of P transposable element transcripts in vivo, leading to the production of the non-transposase-encoding mature mRNA isoform in germ cells. more...