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Items: 2

1.

RNA-seq_D1-MoDC-G

Organism:
Homo sapiens
Source name:
CD14+ Monocytes
Platform:
GPL20301
Series:
GSE120945 GSE130567
Download data: TXT
Sample
Accession:
GSM3743652
ID:
303743652

SRA Run Selector

2.

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate M1-like macrophage polarization [RNA-seq II]

(Submitter supplied) Complete polarization of macrophages towards an M1-like proinflammatory and antimicrobial state requires combined action of IFN-γ and LPS. Synergistic activation of canonical inflammatory NF-κB target genes by IFN-γ and LPS is well appreciated, but less is known about whether IFN-γ negatively regulates components of the LPS response, and how this affects polarization. A combined transcriptomic and epigenomic approach revealed that IFN-γ selectively abrogates LPS-induced feedback and select metabolic pathways by suppressing TLR4-mediated activation of gene enhancers. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
24 Samples
Download data: TAB, TXT
Series
Accession:
GSE130567
ID:
200130567

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

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