U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Links from SRA

Items: 2

1.

ChIP-seq_CBP_IFNg-LPS

Organism:
Homo sapiens
Source name:
Primary human monocyte-derived macrophages
Platform:
GPL11154
Series:
GSE120945 GSE131294
Download data: BIGWIG
Sample
Accession:
GSM3768834
ID:
303768834

SRA Run Selector

2.

IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate M1-like macrophage polarization [ChIP-seq II]

(Submitter supplied) Complete activation of macrophage proinflammatory and antimicrobial phenotype is promoted by combined action of IFN-g and LPS. Synergistic activation of canonical inflammatory NF-kB target genes by IFN-g and LPS is well appreciated, but less is known about whether IFN-g negatively regulates components of the LPS response, and how this affects polarization. A combined transcriptomic and epigenomic approach revealed that IFN-g selectively abrogates LPS-induced feedback and select metabolic pathways by suppressing TLR4-mediated activation of gene enhancers. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: BIGWIG
Series
Accession:
GSE131294
ID:
200131294

PubMed Full text in PMC Similar studies SRA Run Selector

Supplemental Content

Filters: Manage Filters

db=gds|term=|query=10|qty=2|blobid=MCID_670f6a7cc7d3ca20d52e575e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center