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Items: 2

1.

P-S1

Organism:
Homo sapiens
Source name:
induced glioblastoma cells
Platform:
GPL24676
Series:
GSE133509
Download data: H5, HTML
Sample
Accession:
GSM3910556
ID:
303910556
2.

Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development

(Submitter supplied) Many current cellular models aimed to elucidate cancer biology do not recapitulate pathobiology including tumor heterogeneity, an inherent feature of cancer that underlies treatment resistance. Here we introduce a new cancer modeling paradigm using genetically engineered human pluripotent stem cells (hiPSCs) that capture authentic cancer pathobiology. Orthotopic engraftment of the neural progenitor cells derived from hiPSCs introduced with tumor-associated genetic driver mutations revealed by The Cancer Genome Atlas project for glioblastoma (GBM) results in formation of brain tumors. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
14 Samples
Download data: H5, HTML

Supplemental Content

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