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Items: 19

1.

RORa enforces stability of the T-helper-17 cell effector program

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21103 GPL17021
33 Samples
Download data: BW
Series
Accession:
GSE163342
ID:
200163342
2.

RORa enforces stability of the T-helper-17 cell effector program (ChIP-Seq (2))

(Submitter supplied) Chronic inflammation is responsible for a number of debilitating human diseases including inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis. The Th17 subset of T lymphocytes is an important player in the development of these pathogenic conditions. The transcription factor, RORgt was initially coined the master regulator of the Th17 program, but targeting RORgt therapeutically is dangerous owing to an enhanced risk of thymoma upon its inhibition. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21103
6 Samples
Download data: BW
Series
Accession:
GSE163341
ID:
200163341
3.

RORa enforces stability of the T-helper-17 cell effector program (ATAC-Seq)

(Submitter supplied) Chronic inflammation is responsible for a number of debilitating human diseases including inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis. The Th17 subset of T lymphocytes is an important player in the development of these pathogenic conditions. The transcription factor, RORgt was initially coined the master regulator of the Th17 program, but targeting RORgt therapeutically is dangerous owing to an enhanced risk of thymoma upon its inhibition. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
10 Samples
Download data: BW
Series
Accession:
GSE163340
ID:
200163340
4.

DKOIP

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977291
ID:
304977291
5.

AKOIP

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977290
ID:
304977290
6.

WTIP

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977289
ID:
304977289
7.

DKOinput

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977288
ID:
304977288
8.

AKOinput

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977287
ID:
304977287
9.

WTinput

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL21103
Series:
GSE163341 GSE163342
Download data: BW
Sample
Accession:
GSM4977286
ID:
304977286
10.

EAE SC IL17-GFP+

Organism:
Mus musculus
Source name:
Spinal cord
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977285
ID:
304977285
11.

EAE SC IL17-GFP-

Organism:
Mus musculus
Source name:
Spinal cord
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977284
ID:
304977284
12.

SI IL17-GFP+

Organism:
Mus musculus
Source name:
Small intestinal laminapropria
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977283
ID:
304977283
13.

SI IL17-GFP-

Organism:
Mus musculus
Source name:
Small intestinal laminapropria
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977282
ID:
304977282
14.

In vitro 48h Th17 Rep 2

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977281
ID:
304977281
15.

In vitro 48h Th17 Rep 1

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977280
ID:
304977280
16.

In vitro 48h Th2 Rep 2

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977279
ID:
304977279
17.

In vitro 48h Th2 Rep 1

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977278
ID:
304977278
18.

In vitro 48h Th0 Rep 2

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977277
ID:
304977277
19.

In vitro 48h Th0 Rep 1

Organism:
Mus musculus
Source name:
lymphoid organ
Platform:
GPL17021
Series:
GSE163340 GSE163342
Download data: BW
Sample
Accession:
GSM4977276
ID:
304977276
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Supplemental Content

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