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Items: 5

1.

Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing
Platforms:
GPL11002 GPL13112
29 Samples
Download data: WIG
Series
Accession:
GSE42155
ID:
200042155
2.

Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells [ChIP-Seq]

(Submitter supplied) Polycomb repressive complex 2 (PRC2) regulates gene expression during lineage specification through trimethylation of lysine 27 on histone H3 (H3K27me3). In Drosophila, polycomb binding sites are dynamic chromatin regions coupled to incorporation of the histone variant H3.3. Here we show in mouse embryonic stem cells (ESCs) that H3.3 is required for proper establishment of H3K27me3 at the promoters of developmentally regulated genes. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11002 GPL13112
21 Samples
Download data: WIG
Series
Accession:
GSE42152
ID:
200042152
3.

ESC_H33KO1_Jmjd3

Organism:
Mus musculus
Source name:
Embryonic stem cells
Platform:
GPL13112
Series:
GSE42152 GSE42155
Download data: WIG
Sample
Accession:
GSM1207794
ID:
301207794
4.

ESC_H33KO1_UTX

Organism:
Mus musculus
Source name:
Embryonic stem cells
Platform:
GPL13112
Series:
GSE42152 GSE42155
Download data: WIG
Sample
Accession:
GSM1207792
ID:
301207792
5.

ESC_H33KO2_Hira

Organism:
Mus musculus
Source name:
Embryonic stem cells
Platform:
GPL13112
Series:
GSE42152 GSE42155
Download data: WIG
Sample
Accession:
GSM1207790
ID:
301207790
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Supplemental Content

db=gds|term=txid10090[orgn]%20AND%20%22strain%20129/C57Bl/6%20H3%203%20KO%22[All%20Fields]|query=1|qty=2|blobid=MCID_663868a6718719393b4ca85e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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