txid10090[orgn] AND "strain BXD13"[All Fields] - GEO DataSets

Select item 2001131921.

Genome-wide maps of H3K4me3 in C57BL6/J, DBA/2J, and BXD lines for male germ cells, hepatocytes, cardiomyocytes, and mouse ESCs

(Submitter supplied) Here, we have explored how natural genetic variation in mice shapes the epigenome by studying levels of H3K4me3, a mark of active chromatin. We found tissue-specific trans-regulation in four diverse cell types: male germ cells, embryonic stem (ES) cells, hepatocytes and cardiomyocytes. Using recombinant inbred lines, we mapped six major trans-acting histone quantitative trait loci (hQTL) modulating hundreds of H3K4me3 sites in germ cells. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17021 GPL21103
135 Samples

Download data: TXT

Series

Accession:: GSE113192

ID:: 200113192

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000847672.

Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource

(Submitter supplied) The Hippocampus Consortium data set provides estimates of mRNA expression in the adult hippocampus of 99 genetically diverse strains of mice including 67 BXD recombinant inbred strains, 13 CXB recombinant inbred strains, a diverse set of common inbred strains, and two reciprocal F1 hybrids. The hippocampus is an important and intriguing part of the forebrain that is crucial in memory formation and retrieval, and that is often affected in epilepsy, Alzheimer's disease, and schizophrenia. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
201 Samples

Download data: CEL, TXT

Series

Accession:: GSE84767

ID:: 200084767

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000175223.

BXD Mouse Liver Gene Expression

(Submitter supplied) The liver is the primary site for the metabolism of nutrients, drugs, and chemical agents. Although metabolic pathways are complex and tightly regulated, genetic variation among individuals, reflected in variations in gene expression levels, introduces complexity into research on liver disease. This study dissected genetic networks that control liver gene expression through the combination of large-scale quantitative mRNA expression analysis with genetic mapping in a reference population of BXD recombinant inbred mouse strains for which extensive single-nucleotide polymorphism, haplotype, and phenotypic data are publicly available. more...