GEO DataSets

(Submitter supplied) CCA-adding enzymes are highly specific RNA polymerases that synthesize and maintain the sequence CCA at the tRNA 3‘-end. Here, we investigated the impact of cold adaptation on the reactivity and specificity of CCA-adding enzymes from psychrophilic bacteria. A comparative study of the corresponding enzymes from closely related psychro-, meso-, and thermophilic Bacillales indicates that the cold-adapted enzymes show a considerable error rate during CCA synthesis, resulting in additional incorporations of C and A residues. more...

Organism:

Exiguobacterium sibiricum; Planococcus halocryophilus; Geobacillus stearothermophilus; Bacillus subtilis subsp. subtilis str. 168

Type:

Expression profiling by high throughput sequencing

4 related Platforms

23 Samples

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