GEO DataSets

(Submitter supplied) The pathogenic bacterium Chlamydia reproduces via an unusual intracellular developmental cycle in which it converts from a dividing form (reticulate body or RB) to an infectious form (elementary body or EB). The transcription factor Euo has been proposed as a developmental regulator in C. trachomatis because it repressed a number of late chlamydial promoters, which are transcribed during RB-to-EB conversion. more...

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32238

18 Samples

Download data: XLSX

(Submitter supplied) The bacteria in the chlamydiales order are obligate intracellular parasites of eukaryotic cells. They are reliant on an infectious cycle consisting of at least three phenotypically distinct cell forms termed the reticulate body (RB), the intermediate body (IB) and the elementary body (EB). The EB is infectious but does not replicate. The RB replicates in the host cell but is non-infectious, while the IB is an intermediate form that transitions to the EB form. more...

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28812

30 Samples

Download data: TXT

(Submitter supplied) The obligate intracellular bacterium Chlamydia has a unique developmental cycle that alternates between two contrasting cell types. With a hardy envelope and highly condensed genome, the small elementary body (EB) maintains limited metabolic activities yet can survive in an extracellular environment and is infectious. After entering host cells, EBs differentiate into larger and proliferating reticulate bodies (RBs). more...

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28812

12 Samples

Download data: TXT

(Submitter supplied) To determine the role that GrgA plays in chlamydial physiology, we constructed a Chlamydia trachomatis mutant that we term L/cgad-peig, in which the chromosomal grgA (ctl0766 or ct504) has been disrupted by Targetron mutagenesis, and the plasmid carries an inducible grgA under the control of anhydrotetracycline (ATC). RNA-Seq analysis was performed for L2/cgad-peig grown with and without ATC.

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32238

12 Samples

Download data: TXT

(Submitter supplied) RNAseq analysis was performed for C. trachomatis serovar L2 after knocking down or overexpressing different sigma factors.

Organism:

Chlamydia trachomatis L2/434/Bu

Type:

Expression profiling by high throughput sequencing

Platform:

GPL33362

48 Samples

Download data: XLSX

(Submitter supplied) Variations between strains have been extensively studied in human pathogens mainly because even genomically highly identical strains can cause severely different phenotypes in their hosts. Here we investigate within-species diversity in Rhabdochlamydia porcellionis a pathogen infecting terrestrial isopods and a member of the phylum Chlamydia that also includes well-known human pathogens as Chlamydia trachomatis. more...

Organism:

Candidatus Rhabdochlamydia porcellionis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32597

18 Samples

Download data: TXT

(Submitter supplied) The pathogenic bacterium Chlamydia reproduces via an unusual intracellular developmental cycle in which it converts from a dividing form (reticulate body or RB) to an infectious form (elementary body or EB). The transcription factor Euo has been proposed as a developmental regulator in C. trachomatis because it repressed a number of late chlamydial promoters, which are transcribed during RB-to-EB conversion. more...

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32238

16 Samples

Download data: XLSX

(Submitter supplied) The pathogenic bacterium Chlamydia reproduces via an unusual intracellular developmental cycle in which it converts from a dividing form (reticulate body or RB) to an infectious form (elementary body or EB). The transcription factor Euo has been proposed as a developmental regulator in C. trachomatis because it repressed a number of late chlamydial promoters, which are transcribed during RB-to-EB conversion. more...

Organism:

Chlamydia trachomatis

Type:

Other

Platform:

GPL32238

8 Samples

Download data: XLSX

(Submitter supplied) We utilized host-pathogen dual RNA-sequencing to elucidate the transcriptomes of both Chlamydia trachomatis and the infected HeLa cell during nutritional conditions that induce persistence.

Organism:

Chlamydia trachomatis L2/434/Bu; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL30321 GPL30320

18 Samples

Download data: CSV

(Submitter supplied) Heat shock-induced transcriptomic response in Chlamydia trachomatis

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28812

6 Samples

Download data: FA, GTF, TXT

(Submitter supplied) Effects of overexpression of Chlamydia trachomatis transcription factors GrgA, Euo and HrcA on the chlamydial transcriptome were determined.

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28812

36 Samples

Download data: TXT

(Submitter supplied) In this work, we investigated intracellular pH homeostasis within the thermoacidophilc methanotroph Methylacidiphilum sp. RTK17.1. Our findings show the proton motive force for this species is primarily generated by a pH gradient across the cellular membrane. In batch experiments, the addition of formate resulted in no observable cell growth and, correspondingly, acidification of the cytosol, decreased formate dehydrogenase activity and (presumably) cell-death. more...

Organism:

Candidatus Methylacidiphilum infernorum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26766

3 Samples

Download data: TXT

(Submitter supplied) Chlamydia trachomatis D serovar was grown in axenic culture with G6P or G6P with glutamine. The data reveal the early transcriptonal regulation in the bacteria.

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28305

9 Samples

Download data: TXT

(Submitter supplied) Anaerobic ammonium-oxidising (anammox) bacteria, members of the ‘Candidatus Brocadiaceae’ family, play an important role in the nitrogen cycle and are estimated to be responsible for about half of the oceanic nitrogen loss to the atmosphere. Anammox bacteria combine ammonium with nitrite and produce dinitrogen gas via the intermediates nitric oxide and hydrazine (anammox reaction) while nitrate is formed as a by-product. more...

Organism:

Candidatus Kuenenia stuttgartiensis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28427

2 Samples

Download data: CSV

(Submitter supplied) To identify immunodominant antigens that elicit a humoral immune response following a primary genital infection, rhesus monkeys were inoculated cervically with Chlamydia trachomatis serovar D. Serum samples were collected and probed with a protein microarray expressing 864/894 (96.4%) of the open reading frames of the C. trachomatis serovar D genome. The antibody response was analyzed in 72 serum samples from 12 inoculated monkeys. more...

Organism:

Chlamydia trachomatis; Macaca mulatta

Type:

Protein profiling by protein array

Platform:

GPL28497

72 Samples

Download data: TXT

(Submitter supplied) Symbiosis is a ubiquitous phenomenon in nature, and these inter-species interactions have a massive impact on organisms, shaping the world around us today. The relationship between the partners in microbial symbioses have been described as existing along a parasitism-mutualism continuum, and the dynamics of this continuum are dependent upon numerous genotypic and environmental factors. Theoretical and experimental studies show that vertical transmission (VT) leads to the evolution of mutualistic traits, whereas horizontal transmission (HT) facilitates the emergence of parasitic features. more...

Organism:

Parachlamydia acanthamoebae UV-7

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27541

18 Samples

Download data: TXT

(Submitter supplied) Metabolic flexibility in aerobic methane oxidising bacteria (methanotrophs) enhances cell growth and survival in instances where resources are variable or limiting. Examples include the production of intracellular compounds (such as glycogen or polyhydroxyalkanoates) in response to unbalanced growth conditions and the use of some energy substrates, besides methane, when available. Indeed, recent studies show that verrucomicrobial methanotrophs can grow mixotrophically through oxidation of hydrogen and methane gases via respiratory membrane-bound group 1d [NiFe] hydrogenases and methane monooxygenases respectively. more...

Organism:

Candidatus Methylacidiphilum infernorum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26766

5 Samples

Download data: TXT

(Submitter supplied) Legionella pneumophila are important opportunistic pathogens for which environmental reservoirs such as protists are crucial for the infection of humans. Free-living amoebae are considered key hosts providing nutrients and shelter for highly efficient intracellular proliferation of L. pneumophila, which eventually leads to lysis of the amoeba host cell. Yet, the significance of other bacterial players for L. more...

Organism:

Acanthamoeba castellanii; Legionella pneumophila; Candidatus Protochlamydia amoebophila

Type:

Expression profiling by high throughput sequencing

4 related Platforms

22 Samples

Download data: TXT

(Submitter supplied) The pathogenic spirochete Borrelia burgdorferi senses and responds to diverse environmental challenges, including changes in nutrient availability, throughout its natural infectious cycle in Ixodes spp. ticks and mammalian hosts. This study examined the role of the putative DnaK suppressor protein (DksA) in the transcriptional response of B. burgdorferi to starvation. Wild-type and dksA-deficient B. more...

Organism:

Yersinia pestis; Borreliella burgdorferi; Chlamydia trachomatis; Staphylococcus aureus; Coxiella burnetii; Streptococcus pyogenes

Type:

Expression profiling by array

Platform:

GPL2129

12 Samples

Download data: CEL, CHP

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Chlamydia trachomatis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24258

28 Samples

Download data