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Items: 1 to 20 of 229

1.

Drosophila and Commensal Bacteria Synergistically Compete with Opportunistic Pathogens at Bulk and Single-Cell Resolutions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Serratia marcescens; Lactiplantibacillus plantarum
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL33401 GPL30015 GPL34033
30 Samples
Download data: MTX, TSV, TXT
Series
Accession:
GSE251783
ID:
200251783
2.

Drosophila and Commensal Bacteria Synergistically Compete with Opportunistic Pathogens at Bulk and Single-Cell Resolutions [scRNA-seq]

(Submitter supplied) A challenging task to reveal health and disease-associated microbiome signatures is to disentangle regulatory networks of microbes among themselves and with their host. Using the integrated Drosophila-commensal-pathogen model system, we here reported that Drosophila and commensal bacterium L. plantarum cooperated to compete with the opportunistic pathogen S. marcescens. At first, we found that Drosophila larvae and L. more...
Organism:
Serratia marcescens; Lactiplantibacillus plantarum
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL33401 GPL34033 GPL30015
6 Samples
Download data: MTX, TSV
Series
Accession:
GSE251782
ID:
200251782
3.

Drosophila and Commensal Bacteria Synergistically Compete with Opportunistic Pathogens at Bulk and Single-Cell Resolutions [bulkRNA-seq]

(Submitter supplied) A challenging task to reveal health and disease-associated microbiome signatures is to disentangle regulatory networks of microbes among themselves and with their host. Using the integrated Drosophila-commensal-pathogen model system, we here reported that Drosophila and commensal bacterium L. plantarum cooperated to compete with the opportunistic pathogen S. marcescens. At first, we found that Drosophila larvae and L. more...
Organism:
Lactiplantibacillus plantarum; Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL34033 GPL30015 GPL33401
24 Samples
Download data: TXT
Series
Accession:
GSE251781
ID:
200251781
4.

The transcriptional response to low temperature is weakly conserved across Enterobacteriales

(Submitter supplied) Bacteria respond to changes in their external environment like temperature by changing the transcription of their genes, but we know little about how these regulatory patterns evolve. We used RNA-seq to study the transcriptional response of a shift from 37°C to 15°C in wild-type Escherichia coli, Salmonella enterica, Citrobacter rodentium, Enterobacter cloacae, Klebsiella pneumoniae, and Serratia marcescens, as well as ∆rpoS strains of E. more...
Organism:
Citrobacter rodentium; Enterobacter cloacae; Escherichia coli; Klebsiella pneumoniae; Salmonella enterica; Serratia marcescens
Type:
Expression profiling by high throughput sequencing
6 related Platforms
64 Samples
Download data: TXT
Series
Accession:
GSE267531
ID:
200267531
5.

Transcriptomic analyses of bacterial growth on fungal necromass reveals different microbial community niches during degradation

(Submitter supplied) Bacteria are major drivers of organic matter decomposition and play crucial roles in global nutrient cycling. Although the degradation of dead fungal biomass (necromass) is increasingly recognized as an important contributor to soil carbon (C) and nitrogen (N) cycling, the genes and metabolic pathways involved in necromass degradation are under characterized. In particular, how bacteria degrade necromass containing different quantities of melanin, which largely control rates of necromass decomposition in situ, is largely unknown. more...
Organism:
Cellvibrio japonicus; Chitinophaga pinensis; Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL34520 GPL34518 GPL34519
48 Samples
Download data: CSV, XLSX
Series
Accession:
GSE268149
ID:
200268149
6.

Auxin-mediated regulation of susceptibility to toxic metabolites, c-di-GMP levels, and phage infection in the rhizobacterium Serratia plymuthica

(Submitter supplied) To investigate the broader effects of exogenous IAA on gene expression in S. plymuthica A153, we used transcriptome sequencing (RNA-seq) to analyze changes in the global transcriptome of A153 in response to IAA treatment.
Organism:
Serratia plymuthica
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33949
9 Samples
Download data: CSV
Series
Accession:
GSE248473
ID:
200248473
7.

The Host Modulates Transcriptional Profile and Phenotypic Heterogeneity in Symbionts

(Submitter supplied) Host-microbe interactions are virtually bidirectional, benefiting both the host and microbial sides. It is becoming increasingly recognized the influence of the microbe on many aspects of host physiology and diseases, but whether/how the host affects their symbionts is poorly characterized. Here, we reported that the host acts as a critical factor to shape the lifestyle of their symbionts in the Drosophila and bacteria model system. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33401
10 Samples
Download data: TSV
Series
Accession:
GSE232484
ID:
200232484
8.

The Host Modulates Transcriptional Profile and Phenotypic Heterogeneity in Symbionts.

(Submitter supplied) Host-microbe interactions are virtually bidirectional, benefiting both the host and microbial sides. It is becoming increasingly recognized the influence of the microbe on many aspects of host physiology and diseases, but whether/how the host affects their symbionts is poorly characterized. Here, we reported that the host acts as a critical factor to shape the lifestyle of their symbionts in the Drosophila and bacteria model system. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33401
9 Samples
Download data: TXT
Series
Accession:
GSE232120
ID:
200232120
9.

Effect of deletion of the ipdc gene, involved in indole-3-acetic acid synthesis, in the biocontrol agent Serratia plymuthica A153

(Submitter supplied) To explore the role of indole-3-acetic acid (IAA) as signalling molecule in plant-associated bacteria we analyzed the whole transcriptome of S. plymuthica A153 wild type and its Δipdc mutant in vitro
Organism:
Serratia plymuthica
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33188
6 Samples
Download data: TXT
Series
Accession:
GSE226107
ID:
200226107
10.

Transcriptional impact of eepR mutation in Serratia marcescens

(Submitter supplied) The EepR protein is a two-component response regulator protein in the bacterium Serratia marcescens. Mutation of the eepR gene results in pleiotropic changes including reduced expression of secondary metabolites and proteases.
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28109
8 Samples
Download data: TXT
Series
Accession:
GSE155648
ID:
200155648
11.

Global identification of Hfq-bound RNA and transcriptional start site mapping in Serratia marcescens.

(Submitter supplied) In order to identify mRNA and sRNAs associated with the RNA-binding protein Hfq in Serratia marcescens strain Db10, Hfq-bound RNA was immunoprecipitated from a strain encoding an Hfq-3FLAG fusion protein at the normal location and sequenced, in parallel with the wild type strain (no fusion) as negative control. Additionally global transcriptional start site mapping was performed on total RNA, with or without TEX treatment, isolated from wild type Serratia marcescens. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21500
4 Samples
Download data: WIG
Series
Accession:
GSE78185
ID:
200078185
12.

A genome-scale antibiotic screen in Serratia marcescens identifies YdgH as a conserved modifier of cephalosporin and detergent susceptibility

(Submitter supplied) Serratia marcescens, a member of the order Enterobacterales, is adept at colonizing healthcare environments and an important cause of invasive infections. Antibiotic resistance is a daunting problem in S. marcescens because in addition to plasmid-mediated mechanisms, most isolates have considerable intrinsic resistance to multiple antibiotic classes. To discover endogenous modifiers of antibiotic susceptibility in S. more...
Organism:
Serratia marcescens subsp. marcescens ATCC 13880
Type:
Other
Platform:
GPL29934
5 Samples
Download data: XLSX
Series
Accession:
GSE169651
ID:
200169651
13.

Virulence factor expression by Serratia marcescens during microbial keratitis is regulated by stress response protein GumB

(Submitter supplied) The goal of this project was to analyze virulence factor expression during microbial keratitis and to determine the impact of the Rcs system regulator GumB on the transcriptional profile
Organism:
Oryctolagus cuniculus; Serratia marcescens
Type:
Other
Platform:
GPL28651
12 Samples
Download data: RCC
Series
Accession:
GSE155486
ID:
200155486
14.

Serratia marcescens gene expression mediated by EepR, Rcs system, and GntR-family regulator

(Submitter supplied) The goal of this project was to analyze the role of three different transcriptional regulator systems in regulation of gene expression
Organism:
Serratia marcescens
Type:
Other
Platform:
GPL28651
24 Samples
Download data: RCC, TXT
Series
Accession:
GSE152115
ID:
200152115
15.

Transcriptional impact of gumB mutation in Serratia marcescens

(Submitter supplied) The GumB protein is an IgaA-family member that negatively regulates the Rcs stress response system in the bacterium Serratia marcescens. Mutation of the gumB gene results in increased RCs system activity of numerous genes including those involved in flagellar based motility and capsular polysaccharide formation.
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28573
6 Samples
Download data: TXT
Series
Accession:
GSE151031
ID:
200151031
16.

Insight into the regulation of prodigiosin production by temperature in Serratia marcescens through transcriptome analysis

(Submitter supplied) We report the application of transcriptome sequencing technology for high-throughput profiling of Serratia marcescens for producing prodigiosin. By obtaining over 163 million bases of sequence from Serratia marcescens genome DNA, we generated transcriptome -state maps of Serratia marcescens 12h cells, 24h cells, and 36h cells at 30C and 37C,respectively. We explored the mechanism of S. marcescens response temperature regulation at the transcription level through transcriptome sequencing technology. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28109
12 Samples
Download data: TXT
Series
Accession:
GSE144646
ID:
200144646
17.

Transcriptome analysis of gene expression of strains JNB5-1 and SK8-37

(Submitter supplied) RNAseq analysis was performed to evaluate gene expression differences between strains JNB5-1 and SK8-37. S. marcescens JNB5-1 and SK8-37 cells were grown in LB medium for 10 h before harvesting. The collected cells were then treated with RNAprep pure Kit (TIANGEN) to extract total bacterial RNA and delivered to GENEWIZ in dry ice for transcriptome resequencing analysis. For annotation, the genome of S. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26806
2 Samples
Download data: XLSX
Series
Accession:
GSE158829
ID:
200158829
18.

The Serratia marcescens siderophore, serratiochelin, is necessary for full virulence during bloodstream infection

(Submitter supplied) Serratia marcescens is a bacterium frequently found in the environment, but over the last several decades it has evolved into a concerning clinical pathogen, causing fatal bacteremia. To establish such infections, pathogens require specific nutrients; one very limited but essential nutrient is iron. We sought to characterize the iron acquisition systems in S. marcescens isolate UMH9, which was recovered from a clinical bloodstream infection. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28109
4 Samples
Download data: XLSX
Series
Accession:
GSE145587
ID:
200145587
19.

Transcriptome analysis of gene expression of strains JNB5-1 and SK68

(Submitter supplied) RNAseq analysis was performed to evaluate gene expression differences between strains JNB5-1 and SK68. S. marcescens JNB5-1 and SK68 cells were grown in LB medium for 4 h before harvesting. The collected cells were then treated with RNAprep pure Kit (TIANGEN) to extract total bacterial RNA and delivered to GENEWIZ in dry ice for transcriptome resequencing analysis. For annotation, the genome of S. marcescens WW4 (NC_020211.1) was used as reference. more...
Organism:
Serratia marcescens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26806
2 Samples
Download data: TXT
Series
Accession:
GSE149400
ID:
200149400
20.

An XRE-superfamily transcriptional regulator XrpA controls low pH tolerance of Serratia marcescens

(Submitter supplied) The acid tolerance of industrial strains is a significant challenge in the fermentation process. The bacterium Serratia marcescens is part of the Enterobacteriaceae family of eubacteria, which is a potential industrial microorganism. However, the molecular mechanism behind S. marcescens acid resistance is not properly understood. In this study, we screened for novel regulators that respond to acidic conditions by a Tn5G transposon insertion mutagenesis of S. more...
Organism:
Serratia marcescens WW4
Type:
Expression profiling by high throughput sequencing
Platform:
GPL27450
2 Samples
Download data: TXT
Series
Accession:
GSE137185
ID:
200137185
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