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| Status |
Public on Feb 01, 2021 |
| Title |
Gene expression alternations in Qishen Yiqi Dripping Pill-treated rats kidney |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Diabetic rats changes gene exprssion in Qishen Yiqi Dripping Pill-treated rats kidney
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes. Qishen Yiqi Dripping Pill (QYDP) has been reported to be a renal protective drug. However, the mechanisms remain not certain. This study was performed to investigate the mechanisms of the extract. In this study, Sprague Dawley SD rats were fed with a high-fat diet, and injected with streptozotocin (STZ) to generate a diabetic model. Diabetic rats were administered QYDP.
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| Overall design |
We performed microarray analyses of Qishen Yiqi Dripping Pill-treated rats kidney
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| Contributor(s) |
Zhang Q, Xiao X, Zheng J, Li M, Yu M, Ping F, Wang Z, Qi C, Wang T, Wang X |
| Citation(s) |
33679423 |
| Submission date |
Jul 10, 2019 |
| Last update date |
Mar 11, 2021 |
| Contact name |
Qian Zhang |
| Organization name |
Peking Union Medical College Hospital
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| Street address |
No. 1 Shuaifuyuan, Dongcheng District
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| City |
Beijing |
| ZIP/Postal code |
100730 |
| Country |
China |
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| Platforms (1) |
| GPL17117 |
[RaGene-2_0-st] Affymetrix Rat Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| GSM3935928 |
kidney_Qishen Yiqi Dripping Pill-treated_rep1 [D9] |
| GSM3935929 |
kidney_Qishen Yiqi Dripping Pill-treated_rep2 [F9] |
| GSM3935930 |
kidney_Qishen Yiqi Dripping Pill-treated_rep3 [D10] |
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| Relations |
| BioProject |
PRJNA553686 |
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