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| Status |
Public on Oct 12, 2019 |
| Title |
RNA-seq analysis using glomeruli isolated from control and podocyte-specific bPIX deficient mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We found that podocyte-specific bPIX deficient (KO) mice developed progressive proteinuria starting at ~8 weeks of age, and glomerulosclerosis and podocyte loss by 13 weeks of age. To investigate the mechanism of podocyte loss induced by bPIX deficiency, we analyzed mRNA expression by RNA-sequence using isolated glomeruli from control (CTRL) and KO mice.
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| Overall design |
mRNA profiles of glomeruli isolated from 3 CTRL and 3 podocyte-specific bPIX KO mice were generated.
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| Contributor(s) |
Matsuda J, Takano T |
| Citation missing |
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| |
| Submission date |
Oct 11, 2019 |
| Last update date |
Oct 15, 2019 |
| Contact name |
Tomoko Takano |
| E-mail(s) |
tomoko.takano@mcgill.ca
|
| Phone |
5149341934
|
| Organization name |
McGill University Health Centre (MUHC)
|
| Department |
Department of Medicine
|
| Lab |
Division of Experimental Medicine
|
| Street address |
1001 Decarie Boulevard
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H4A 3J1 |
| Country |
Canada |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA577113 |
| SRA |
SRP225211 |
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