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Series GSE174392 Query DataSets for GSE174392
Status Public on Feb 18, 2022
Title Olig2 Defines a Unique Subset of Neural Stem Cells That Produce Specific Olfactory Bulb Interneuron Subtypes in the Subventricular Zone of Postnatal and Adult Mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Distinct neural stem cells reside in different regions of the subventricular zone and generate multiple olfactory bulb interneuron subtypes in the adult mouse brain. This study shows that the basic helix-loop-helix type transcription factor Olig2 defines a ventrally enriched subset of NSCs in the early postnatal and adult SVZ and plays an important role in the subtype specification of olfactory bulb interneurons produced by adult NSCs.
Overall design E18.5, P14 and adult mouse NSCs were analyzed using 10X single-cell rna-seq
Contributor(s) Adam M, Campbell K, Nakafuku M
Citation(s) 35132995
Submission date May 13, 2021
Last update date May 20, 2022
Contact name Steve Potter
Organization name Cincinnati Children's Hospital Research Foundation
Department Developmental Biology
Street address 240 Albert Sabin Way
City Cincinnati
State/province Ohio
ZIP/Postal code 45229
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (6)
GSM5293528 10X E18.5 VT 01
GSM5293529 10X E18.5 VT 02
GSM5293530 10X P14 SVZ 01
BioProject PRJNA729735
SRA SRP319681

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Supplementary file Size Download File type/resource
GSE174392_RAW.tar 1.2 Gb (http)(custom) TAR (of MTX, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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