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| Status |
Public on Sep 27, 2023 |
| Title |
Gene expression profile, population of macrophages and lymphocytes of the spleen in conditions of liver regeneration after 70% resection in mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The aim of our work was to study the expression profile of spleen genes during liver regeneration, to identify possible biologically active substances that affect reparative processes and inflammation in other organs, as well as the state of the monocytic-macrophage and lymphocytic population of the spleen after liver resection.
We used microarrays for comparison of spleen gene expression on different time periods after 70% liver resection
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| Overall design |
4 groups were studied: the control group - intact spleen, spleen in a 1 day, 3 days and 7 days after liver resection. Each group included 3-6 samples.
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| Contributor(s) |
Kuznetsova M, Vishnyakova P |
| Citation(s) |
37745290 |
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| Submission date |
May 15, 2023 |
| Last update date |
Sep 28, 2023 |
| Contact name |
Polina Vishnyakova |
| E-mail(s) |
vpa2002@mail.ru
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| Organization name |
National Medical Research Center for Obstetrics, Gynecology and Perinatology
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| Street address |
Oparina 4
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| City |
Moscow |
| ZIP/Postal code |
116571 |
| Country |
Russia |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (15)
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| GSM7349922 |
1 day resected spleen, biological rep 1 |
| GSM7349923 |
1 day resected spleen, biological rep 2 |
| GSM7349924 |
1 day resected spleen, biological rep 3 |
| GSM7349925 |
7 days resected spleen, biological rep 1 |
| GSM7349926 |
7 days resected spleen, biological rep 2 |
| GSM7349927 |
7 days resected spleen, biological rep 3 |
| GSM7349928 |
intact spleen, biological rep 4 |
| GSM7349929 |
intact spleen, biological rep 5 |
| GSM7349930 |
intact spleen, biological rep 6 |
| GSM7349931 |
3 days resected spleen, biological rep 1 |
| GSM7349932 |
3 days resected spleen, biological rep 2 |
| GSM7349933 |
3 days resected spleen, biological rep 3 |
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| Relations |
| BioProject |
PRJNA972679 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE232531_RAW.tar |
19.1 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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