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| Status |
Public on Jun 22, 2011 |
| Title |
Gene expression comparison among spleen dendritic cells, brain microglia, brain dendritic cells and bone marrow monocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To understand the functional relationship between brain dendritic cells (brain DCs) and other myeloid cells, we compared the gene expression profile of m/chDCs to that of bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. In order to obtain enough brain DCs for mRNA extraction, we expanded brain DCs with in vivo Flt3L treatment before purification.
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| Overall design |
This study includes data from FACs Aria-purified brain DCs, bone marrow monocytes, brain microglia and classical spleen CD8+ and CD8- DCs. The genearray was performed to compare expression of cell surface endocytic receptor, cytokine receptors, TLRs, transcription factors, molecules for antigen processing and presentation. Each Series consists of 3 individuall samples
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| |
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| Contributor(s) |
Liu K, Meridith MM |
| Citation(s) |
21788405 |
| |
| Submission date |
Jun 13, 2011 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Kang Liu |
| E-mail(s) |
kl2529@columbia.edu
|
| Phone |
212 305-0839
|
| Fax |
212 305-0839
|
| Organization name |
Columbia University
|
| Department |
Microbiology
|
| Lab |
Liu
|
| Street address |
701 W. 168 ST., HHSC Rm. 1302
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10032 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA140789 |
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