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Series GSE41420 Query DataSets for GSE41420
Status Public on Oct 10, 2012
Title A comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary Effects of soy isoflavones, genistein and daidzein, on the hepatic gene expression profile and indices for lipid metabolism were compared in rats.
The GeneChip data was normalized and summarized by using SuperNORM data service (Skylight Biotech Inc.). Significance of expressional change among groups was tested by 2-way ANOVA on the normalized CEL data, which was deposited in a tab-separated ASCII text format. Principal components were identified on the summarized gene data.
Overall design Three groups of rats were fed with an experimental diet containing 2 g/kg of either genistein or daidzein, or a control diet free of isoflavone for 14 days. The basal composition of the experimental diet was (in g/kg): casein, 200; palm oil, 100; corn starch, 150; cellulose, 20; mineral mixture (AIN-93G), 35; vitamin mixture (AIN-93), 10; L-cystine, 3.0; choline bitartrate, 2.0 and sucrose to 1 kg.
Contributor(s) Takahashi Y, Odbayar T, Ide T, Konishi T
Citation(s) 19430610
Submission date Oct 09, 2012
Last update date Jul 31, 2017
Contact name Tomokazu Konishi
Phone +81-18-872-1603
Organization name Akita Prefectural University
Department Bioresource Sciences
Lab Molecular Genetics
Street address Shimoshinjyo Nishi
City Akita
State/province Akita
ZIP/Postal code 010-0195
Country Japan
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (15)
GSM1016819 Non-isoflavone diet, biological rep1
GSM1016820 Non-isoflavone diet, biological rep2
GSM1016821 Non-isoflavone diet, biological rep3
BioProject PRJNA176925

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41420_RAW.tar 35.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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