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| Status |
Public on Oct 24, 2016 |
| Title |
Identification of a macrophage PPARĪ³-GDF3 regulatory axis controlling muscle regeneration |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Muscle injury was elicited by cardiotoxin injection into the tibialis anterior muscle. Macrophages were isolated 2 days post-injury from the regenerating muscle.
We used microarray to obtain global gene expression data of muscle-derived tissue macrophage subsets.
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| Overall design |
Tissue macrophages were collected from regenerating muscle samples of three animals, Ly6C+ F4/80low and Ly6C- F4/80high macrophage subsets were sorted. The global gene expression patterns of distinct macrophage subsets were analyzed on Affymetrix microarrays.
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| Contributor(s) |
Varga T, Nagy L |
| Citation(s) |
34846534 |
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| Submission date |
Jul 21, 2015 |
| Last update date |
Dec 10, 2021 |
| Contact name |
Szilard Poliska |
| E-mail(s) |
poliska@dote.hu
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| Phone |
+3652416432
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| Organization name |
University of Debrecen
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| Department |
Biochemistry and Molecular Biology
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| Lab |
Nuclear Hormone Receptor Research Laboratory
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| Street address |
Egyetem ter 1.
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| City |
Debrecen |
| ZIP/Postal code |
H-4012 |
| Country |
Hungary |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (44)
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| GSM1828601 |
WT_Ly6C+ F4/80low, biological rep1, non-treated, day 1 |
| GSM1828602 |
WT_Ly6C+ F4/80low, biological rep2, non-treated, day 1 |
| GSM1828603 |
WT_Ly6C+ F4/80low, biological rep3, non-treated, day 1 |
| GSM1828604 |
WT_Ly6C+ F4/80low, biological rep4, non-treated, day 1 |
| GSM1828605 |
KO_Ly6C+ F4/80low, biological rep1, non-treated, day 1 |
| GSM1828606 |
KO_Ly6C+ F4/80low, biological rep2, non-treated, day 1 |
| GSM1828607 |
KO_Ly6C+ F4/80low, biological rep3, non-treated, day 1 |
| GSM1828608 |
KO_Ly6C+ F4/80low, biological rep4, non-treated, day 1 |
| GSM1828609 |
WT_Ly6C+ F4/80low, biological rep1, non-treated, day 2 |
| GSM1828610 |
WT_Ly6C+ F4/80low, biological rep2, non-treated, day 2 |
| GSM1828611 |
WT_Ly6C+ F4/80low, biological rep3, non-treated, day 2 |
| GSM1828612 |
WT_Ly6C+ F4/80low, biological rep4, non-treated, day 2 |
| GSM1828613 |
WT_Ly6C+ F4/80low, biological rep5, non-treated, day 2 |
| GSM1828614 |
WT_Ly6C+ F4/80low, biological rep6, non-treated, day 2 |
| GSM1828615 |
WT_Ly6C- F4/80high, biological rep1, non-treated, day 2 |
| GSM1828616 |
WT_Ly6C- F4/80high, biological rep2, non-treated, day 2 |
| GSM1828617 |
WT_Ly6C- F4/80high, biological rep3, non-treated, day 2 |
| GSM1828618 |
WT_Ly6C- F4/80high, biological rep4, non-treated, day 2 |
| GSM1828619 |
WT_Ly6C- F4/80high, biological rep5, non-treated, day 2 |
| GSM1828620 |
WT_Ly6C- F4/80high, biological rep6, non-treated, day 2 |
| GSM1828621 |
KO_Ly6C+ F4/80low, biological rep1, non-treated, day 2 |
| GSM1828622 |
KO_Ly6C+ F4/80low, biological rep2, non-treated, day 2 |
| GSM1828623 |
KO_Ly6C+ F4/80low, biological rep3, non-treated, day 2 |
| GSM1828624 |
KO_Ly6C+ F4/80low, biological rep4, non-treated, day 2 |
| GSM1828625 |
KO_Ly6C+ F4/80low, biological rep5, non-treated, day 2 |
| GSM1828626 |
KO_Ly6C- F4/80high, biological rep1, non-treated, day 2 |
| GSM1828627 |
KO_Ly6C- F4/80high, biological rep2, non-treated, day 2 |
| GSM1828628 |
KO_Ly6C- F4/80high, biological rep3, non-treated, day 2 |
| GSM1828629 |
KO_Ly6C- F4/80high, biological rep4, non-treated, day 2 |
| GSM1828630 |
KO_Ly6C- F4/80high, biological rep5, non-treated, day 2 |
| GSM1828631 |
WT_Ly6C+ F4/80low, biological rep1, rosiglitazone, day 2 |
| GSM1828632 |
WT_Ly6C+ F4/80low, biological rep2, rosiglitazone, day 2 |
| GSM1828633 |
WT_Ly6C+ F4/80low, biological rep3, rosiglitazone, day 2 |
| GSM1828634 |
WT_Ly6C- F4/80high, biological rep1, rosiglitazone, day 2 |
| GSM1828635 |
WT_Ly6C- F4/80high, biological rep2, rosiglitazone, day 2 |
| GSM1828636 |
WT_Ly6C- F4/80high, biological rep3, rosiglitazone, day 2 |
| GSM1828637 |
WT_Ly6C+ F4/80low, biological rep1, non-treated, day 4 |
| GSM1828638 |
WT_Ly6C+ F4/80low, biological rep2, non-treated, day 4 |
| GSM1828639 |
WT_Ly6C+ F4/80low, biological rep3, non-treated, day 4 |
| GSM1828640 |
WT_Ly6C+ F4/80low, biological rep4, non-treated, day 4 |
| GSM1828641 |
KO_Ly6C+ F4/80low, biological rep1, non-treated, day 4 |
| GSM1828642 |
KO_Ly6C+ F4/80low, biological rep2, non-treated, day 4 |
| GSM1828643 |
KO_Ly6C+ F4/80low, biological rep3, non-treated, day 4 |
| GSM1828644 |
KO_Ly6C+ F4/80low, biological rep4, non-treated, day 4 |
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| Relations |
| BioProject |
PRJNA290462 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE71155_RAW.tar |
192.2 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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