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| Status |
Public on May 12, 2017 |
| Title |
Expression Profiling of Term Placenta in Viviparous Mammals by RNA-Seq |
| Organisms |
Dasypus novemcinctus; Ateles fusciceps; Pan paniscus; Canis lupus familiaris; Loxodonta africana; Bos taurus; Mus musculus; Monodelphis domestica |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The placenta is arguably the most anatomically variable organ in mammals. Understanding gene expression patterns among placentas from multiple species can illuminate the molecular basis of placenta function as well as potentially enrich our knowledge of the biology of obstetrical syndromes. We measured the expression profiles of the term placenta of multiple therian mammals using RNA-Seq. We identified multiple genes and transcripts which are differentially expressed across lineages including prolactin, relaxin, and galectins, as well as identifying the non-housekeeping genes which are core to placenta function (such as components of annexin complexes) in all species studied.
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| |
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| Overall design |
RNAseq data from term placentas of 8 species with one sample per species
|
| Web link |
http://www.sciencedirect.com/science/article/pii/S0143400417302369
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| |
|
| Contributor(s) |
Armstrong DL, Wildman D |
| Citation missing |
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| |
| Submission date |
Mar 11, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Don Leigh Armstrong |
| E-mail(s) |
don@donarmstrong.com
|
| Organization name |
University of Illinois at Urbana Champaign
|
| Department |
Institute for Genomic Biology
|
| Lab |
Computing Genomes for Reproductive Health
|
| Street address |
1206 W Gregory Drive
|
| City |
Urbana |
| State/province |
IL |
| ZIP/Postal code |
61801 |
| Country |
USA |
| |
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| Platforms (8)
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| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
| GPL11153 |
Illumina Genome Analyzer II (Bos taurus) |
| GPL13923 |
Illumina Genome Analyzer II (Dasypus novemcinctus) |
| GPL17258 |
Illumina Genome Analyzer II (Monodelphis domestica) |
| GPL18701 |
Illumina Genome Analyzer II (Canis lupus familiaris) |
| GPL21584 |
Illumina Genome Analyzer II (Ateles fusciceps) |
| GPL21585 |
Illumina Genome Analyzer II (Pan paniscus) |
| GPL21586 |
Illumina Genome Analyzer II (Loxodonta africana) |
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| Samples (8)
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|
| Relations |
| BioProject |
PRJNA314981 |
| SRA |
SRP071663 |
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