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Status |
Public on Jan 02, 2017 |
Title |
Major differences between human atopic dermatitis and murine models as determined by global genomic profiling |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array Third-party reanalysis
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Summary |
In this study we applied genomic profiling to evaluate the transcriptomic differences between murine models ot atopic dermatitis. We evaluated the expression data of five models and their respective controls, and one previously published murine dataset (GSE50400). The included models were groupe 1 (Lesional: Flaky tail and FLG mutant; Control: C57BL/6NCrSlc), Group 2 (Lesional: NC/Nga(+mite); Control: NC/Nga(-mite)), Group 3 (Lesional: OVA-ODT 24h; Control: C57BL/6NCrSlc), and Group 4 (Lesional: OXA 2h; Control: BALB/c,Acetone).
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Overall design |
Expression profiles for mice with five murine models were contrasted to their respective controls.
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Contributor(s) |
Ewald DA, Suárez-Fariñas M, Litman TW |
Citation(s) |
27702671 |
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Submission date |
May 04, 2016 |
Last update date |
Nov 22, 2019 |
Contact name |
David Adrian Ewald |
E-mail(s) |
ewald@cbs.dtu.dk
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Organization name |
Technical University of Denmark
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Department |
Department of Systems Biology
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Lab |
Regulatory Genomics
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Street address |
Building 208
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City |
Kongens Lyngby |
ZIP/Postal code |
DK-2800 |
Country |
Denmark |
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Platforms (2) |
GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
GPL17400 |
[MoGene-2_1-st] Affymetrix Mouse Gene 2.1 ST Array [transcript (gene) version] |
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Samples (37)
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Relations |
Reanalysis of |
GSM1218165 |
Reanalysis of |
GSM1218166 |
Reanalysis of |
GSM1218167 |
Reanalysis of |
GSM1218168 |
Reanalysis of |
GSM1218169 |
Reanalysis of |
GSM1218170 |
Reanalysis of |
GSM1218171 |
Reanalysis of |
GSM1218172 |
Reanalysis of |
GSM1218173 |
Reanalysis of |
GSM1218174 |
BioProject |
PRJNA321115 |