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| Status |
Public on Jul 15, 2016 |
| Title |
Expression data from uterus tissue of sheep |
| Organism |
Ovis aries |
| Experiment type |
Expression profiling by array
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| Summary |
Embryo implantation is an essential step for the establishment of pregnancy and is crucial for the successful embryo transplantation of in vitro fertilization embryos. The successful implantation of an embryo depends upon cellular and molecular dialog between the uterus and the embryo.
We used microarrays to detail the key regulated genes underlying embryo implantation process in sheep.
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| Overall design |
In this study, all ewes were assigned to two experimental groups randomly as follows: in vivo embryo (IVV) group (n = 12) and in vitro embryo (IVT) group (n = 9). The ewes of IVV group were mated with fertile rams of the same strain to induce pregnancy respectively. In addition, the ewes of IVT group were transplanted 3 in vitro fertilization (IVF) embryos at 4 ~ 8 cell stage respectively after synchronization of estrus. Uterus tissue at implantation and inter-implantation sites of both groups were collected at successive stages of implantation period and used for microarray analysis.
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| Contributor(s) |
Guo Y, Ni H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 14, 2016 |
| Last update date |
Jul 17, 2016 |
| Contact name |
Xihui Sheng |
| E-mail(s) |
shengxh03@163.com
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| Organization name |
Beijing university of agriculture
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| Street address |
No.7 Beinong Road, Huilongguan Town, Changping District
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| City |
Beijing |
| ZIP/Postal code |
102206 |
| Country |
China |
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| Platforms (1) |
| GPL19480 |
[OviGene-1_1-st] Ovine Gene 1.1 ST Array [transcript (gene) version] |
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| Samples (8)
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| GSM2233406 |
implantation sites on day 10 in IVV group |
| GSM2233407 |
inter-implantation sites on day 10 in IVV group |
| GSM2233408 |
implantation sites on day 12 in IVV group |
| GSM2233409 |
implantation sites on day 12 in IVT group |
| GSM2233410 |
implantation sites on day 14 in IVV group |
| GSM2233411 |
implantation sites on day 14 in IVT group |
| GSM2233412 |
implantation sites on day 16 in IVV group |
| GSM2233413 |
implantation sites on day 16 in IVT group |
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| Relations |
| BioProject |
PRJNA329122 |
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