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Series GSE96879 Query DataSets for GSE96879
Status Public on Mar 21, 2020
Title Epigenome-Wide Methylation Profile in sustemic lupus erythematosus: Impact of ethnicity and SLEDAI score
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Epienome-wide DNA methylation profiling of systemic lupus erythematosus (SLE). The Illumina HumanMethylation450K Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs in normal human blood samples from females. Samples included 33 non-SLE female patients (control) and 57 SLE female patients. SLE patients:- Ethnicity included 39 African americans and 18 European Americans. SLEDAI score ranged from 2-30. Non-SLE pateients:-Ethnicity indclued 17 African Americans and 16 European Americans, all with a SLEDAI score of zero.
 
Overall design Bisulphite converted DNA from the 90 samples were hybridized to the Illumina Infinium HumanMethylation450K Beadchip
 
Contributor(s) Joseph S, Green-Knox B, George NI, Lyn-Cook B
Citation(s) 30301579
Submission date Mar 21, 2017
Last update date Jun 22, 2020
Contact name Stancy Joseph
E-mail(s) stancy.joseph@fda.hhs.gov
Phone 8705437502
Organization name FDA/NCTR
Department Biochemical Toxicology
Street address 3900 NCTR Road
City Jefferson
State/province Ar
ZIP/Postal code 72079
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (90)
GSM2545485 Genomic DNA from peripheral blood monoculear cells 1
GSM2545486 Genomic DNA from peripheral blood monoculear cells 3
GSM2545487 Genomic DNA from peripheral blood monoculear cells 5
Relations
BioProject PRJNA379978

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE96879_RAW.tar 2.3 Gb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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