|
Status |
Public on Jun 07, 2023 |
Title |
THIOxenoHCC_roi16_seg006_otherLeukocytes |
Sample type |
protein |
|
|
Source name |
THIOxenoHCC_roi16_seg006_otherLeukocytes
|
Organism |
Mus musculus |
Characteristics |
segment_type: Other leukocytes (CD3-/CD45+) morphology_marker_cd3: negative morphology_marker_cd45: positive morphology_marker_panck: negative treatment: THIO
|
Treatment protocol |
Mice were treated with vehicle control, THIO, anti-PD-L1+anti-VEGF, or anti-PD-L1+anti-VEGF+THIO and sacrificed at the end of the treatment (n=1 per group).
|
Growth protocol |
na
|
Extracted molecule |
protein |
Extraction protocol |
na
|
Label |
fluorescent barcode
|
Label protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
|
|
Hybridization protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
Scan protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
Description |
protein on FFPE tissue section
|
Data processing |
Raw count data of antibody-captured protein copy numbers in each segment were normalized by scaling with geometric mean of the counts of the housekeeping proteins
|
|
|
Submission date |
Nov 30, 2022 |
Last update date |
Jun 07, 2023 |
Contact name |
Yujin Hoshida |
E-mail(s) |
Yujin.Hoshida@UTSouthwestern.edu
|
Organization name |
University of Texas Southwestern Medical Center
|
Street address |
5323 Harry Hines Blvd
|
City |
Dallas |
State/province |
TX |
ZIP/Postal code |
75390 |
Country |
USA |
|
|
Platform ID |
GPL32902 |
Series (1) |
GSE219108 |
Digital Spatial Profiling of immuno-oncology proteins in mouse hepatocellular carcinoma xenograft treated with THIO-based combination immune therapie |
|