|
| Status |
Public on Jun 07, 2023 |
| Title |
THIOxenoHCC_roi24_seg008_HCCandStroma |
| Sample type |
protein |
| |
|
| Source name |
THIOxenoHCC_roi24_seg008_HCCandStroma
|
| Organism |
Mus musculus |
| Characteristics |
segment_type: HCC/stromal cells (CD3-/CD45-/PanCK+/-)
morphology_marker_cd3: negative
morphology_marker_cd45: negative
morphology_marker_panck: positive
treatment: anti-PD-L1 + anti-VEGF + THIO
|
| Treatment protocol |
Mice were treated with vehicle control, THIO, anti-PD-L1+anti-VEGF, or anti-PD-L1+anti-VEGF+THIO and sacrificed at the end of the treatment (n=1 per group).
|
| Growth protocol |
na
|
| Extracted molecule |
protein |
| Extraction protocol |
na
|
| Label |
fluorescent barcode
|
| Label protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
| |
|
| Hybridization protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
| Scan protocol |
Refer to the NanoString Digital Spatial Profiling (DSP) GeoMx analysis manuals
|
| Description |
protein on FFPE tissue section
|
| Data processing |
Raw count data of antibody-captured protein copy numbers in each segment were normalized by scaling with geometric mean of the counts of the housekeeping proteins
|
| |
|
| Submission date |
Nov 30, 2022 |
| Last update date |
Jun 07, 2023 |
| Contact name |
Yujin Hoshida |
| E-mail(s) |
Yujin.Hoshida@UTSouthwestern.edu
|
| Organization name |
University of Texas Southwestern Medical Center
|
| Street address |
5323 Harry Hines Blvd
|
| City |
Dallas |
| State/province |
TX |
| ZIP/Postal code |
75390 |
| Country |
USA |
| |
|
| Platform ID |
GPL32902 |
| Series (1) |
| GSE219108 |
Digital Spatial Profiling of immuno-oncology proteins in mouse hepatocellular carcinoma xenograft treated with THIO-based combination immune therapie |
|
