U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neurosis

MedGen UID:
10334
•Concept ID:
C0027932
•
Mental or Behavioral Dysfunction
Synonyms: Disorder, Neurotic; Disorders, Neurotic; Neuroses; Neurotic Disorder; Neurotic Disorders; Psychoneuroses
SNOMED CT: Neurotic disorder (111475002); Neurosis (111475002); Nonpsychotic mental disorder (111475002)

Definition

A form of functional mental illness that manifests in distressed emotional reactions such as anxiety, obsessive thoughts, compulsive behaviors, or irrational fears. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurosis

Professional guidelines

PubMed

Antidepressants for treatment of depression in primary care: a systematic review and meta-analysis.
Arroll B, Chin WY, Martis W, Goodyear-Smith F, Mount V, Kingsford D, Humm S, Blashki G, MacGillivray S
J Prim Health Care 2016 Dec;8(4):325-334. doi: 10.1071/HC16008. PMID: 29530157
A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children/adolescents and adults.
Skapinakis P, Caldwell D, Hollingworth W, Bryden P, Fineberg N, Salkovskis P, Welton N, Baxter H, Kessler D, Churchill R, Lewis G
Health Technol Assess 2016 Jun;20(43):1-392. doi: 10.3310/hta20430. PMID: 27306503Free PMC Article
Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder.
Cipriani A, Reid K, Young AH, Macritchie K, Geddes J
Cochrane Database Syst Rev 2013 Oct 17;2013(10):CD003196. doi: 10.1002/14651858.CD003196.pub2. PMID: 24132760Free PMC Article

Recent clinical studies

Etiology

Psychological interventions for individuals with cystic fibrosis and their families.
Goldbeck L, Fidika A, Herle M, Quittner AL
Cochrane Database Syst Rev 2014 Jun 18;2014(6):CD003148. doi: 10.1002/14651858.CD003148.pub3. PMID: 24941199Free PMC Article
Passiflora for anxiety disorder.
Miyasaka LS, Atallah AN, Soares BG
Cochrane Database Syst Rev 2007 Jan 24;(1):CD004518. doi: 10.1002/14651858.CD004518.pub2. PMID: 17253512
Valerian for anxiety disorders.
Miyasaka LS, Atallah AN, Soares BG
Cochrane Database Syst Rev 2006 Oct 18;(4):CD004515. doi: 10.1002/14651858.CD004515.pub2. PMID: 17054208
Migration and depression.
Bhugra D
Acta Psychiatr Scand Suppl 2003;(418):67-72. doi: 10.1034/j.1600-0447.108.s418.14.x. PMID: 12956818
Psychosurgery today.
Laitinen LV
Acta Neurochir Suppl (Wien) 1988;44:158-62. doi: 10.1007/978-3-7091-9005-0_30. PMID: 3066132

Diagnosis

Psychogenic voice disorders.
Kosztyła-Hojna B, Moskal D, Łobaczuk-Sitnik A, Kraszewska A, Zdrojkowski M, Biszewska J, Skorupa M
Otolaryngol Pol 2018 Jun 12;72(4):26-34. doi: 10.5604/01.3001.0012.0636. PMID: 30190444
The history of generalized anxiety disorder as a diagnostic category.
Crocq MA
Dialogues Clin Neurosci 2017 Jun;19(2):107-116. doi: 10.31887/DCNS.2017.19.2/macrocq. PMID: 28867935Free PMC Article
Passiflora for anxiety disorder.
Miyasaka LS, Atallah AN, Soares BG
Cochrane Database Syst Rev 2007 Jan 24;(1):CD004518. doi: 10.1002/14651858.CD004518.pub2. PMID: 17253512
Valerian for anxiety disorders.
Miyasaka LS, Atallah AN, Soares BG
Cochrane Database Syst Rev 2006 Oct 18;(4):CD004515. doi: 10.1002/14651858.CD004515.pub2. PMID: 17054208
Castration.
Rangell L
J Am Psychoanal Assoc 1991;39(1):3-23. doi: 10.1177/000306519103900101. PMID: 2026855

Therapy

Dance movement therapy for depression.
Meekums B, Karkou V, Nelson EA
Cochrane Database Syst Rev 2015 Feb 19;2015(2):CD009895. doi: 10.1002/14651858.CD009895.pub2. PMID: 25695871Free PMC Article
Exercise for depression.
Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo M, Mead GE
Cochrane Database Syst Rev 2013 Sep 12;2013(9):CD004366. doi: 10.1002/14651858.CD004366.pub6. PMID: 24026850Free PMC Article
Interventions for vaginismus.
Melnik T, Hawton K, McGuire H
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD001760. doi: 10.1002/14651858.CD001760.pub2. PMID: 23235583Free PMC Article
Sertraline versus other antidepressive agents for depression.
Cipriani A, La Ferla T, Furukawa TA, Signoretti A, Nakagawa A, Churchill R, McGuire H, Barbui C
Cochrane Database Syst Rev 2010 Apr 14;(4):CD006117. doi: 10.1002/14651858.CD006117.pub4. PMID: 20393946Free PMC Article
Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis.
UK ECT Review Group
Lancet 2003 Mar 8;361(9360):799-808. doi: 10.1016/S0140-6736(03)12705-5. PMID: 12642045

Prognosis

Research on religion, spirituality, and mental health: a review.
Koenig HG
Can J Psychiatry 2009 May;54(5):283-91. doi: 10.1177/070674370905400502. PMID: 19497160
Migration and depression.
Bhugra D
Acta Psychiatr Scand Suppl 2003;(418):67-72. doi: 10.1034/j.1600-0447.108.s418.14.x. PMID: 12956818
Post whiplash syndrome.
Bogduk N
Aust Fam Physician 1994 Dec;23(12):2303-7. PMID: 7848143
Psychosurgery today.
Laitinen LV
Acta Neurochir Suppl (Wien) 1988;44:158-62. doi: 10.1007/978-3-7091-9005-0_30. PMID: 3066132
Hypochondriacal states.
Kenyon FE
Br J Psychiatry 1976 Jul;129:1-14. doi: 10.1192/bjp.129.1.1. PMID: 779913

Clinical prediction guides

Vortioxetine for depression in adults.
Koesters M, Ostuzzi G, Guaiana G, Breilmann J, Barbui C
Cochrane Database Syst Rev 2017 Jul 5;7(7):CD011520. doi: 10.1002/14651858.CD011520.pub2. PMID: 28677828Free PMC Article
Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis.
Ng QX, Venkatanarayanan N, Ho CY
J Affect Disord 2017 Mar 1;210:211-221. Epub 2017 Jan 3 doi: 10.1016/j.jad.2016.12.048. PMID: 28064110
A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children/adolescents and adults.
Skapinakis P, Caldwell D, Hollingworth W, Bryden P, Fineberg N, Salkovskis P, Welton N, Baxter H, Kessler D, Churchill R, Lewis G
Health Technol Assess 2016 Jun;20(43):1-392. doi: 10.3310/hta20430. PMID: 27306503Free PMC Article
Reiki for depression and anxiety.
Joyce J, Herbison GP
Cochrane Database Syst Rev 2015 Apr 3;(4):CD006833. doi: 10.1002/14651858.CD006833.pub2. PMID: 25835541
Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials.
Miroddi M, Calapai G, Navarra M, Minciullo PL, Gangemi S
J Ethnopharmacol 2013 Dec 12;150(3):791-804. Epub 2013 Oct 17 doi: 10.1016/j.jep.2013.09.047. PMID: 24140586

Recent systematic reviews

Exercise for depression.
Cooney GM, Dwan K, Greig CA, Lawlor DA, Rimer J, Waugh FR, McMurdo M, Mead GE
Cochrane Database Syst Rev 2013 Sep 12;2013(9):CD004366. doi: 10.1002/14651858.CD004366.pub6. PMID: 24026850Free PMC Article
Interventions for vaginismus.
Melnik T, Hawton K, McGuire H
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD001760. doi: 10.1002/14651858.CD001760.pub2. PMID: 23235583Free PMC Article
Sertraline versus other antidepressive agents for depression.
Cipriani A, La Ferla T, Furukawa TA, Signoretti A, Nakagawa A, Churchill R, McGuire H, Barbui C
Cochrane Database Syst Rev 2010 Apr 14;(4):CD006117. doi: 10.1002/14651858.CD006117.pub4. PMID: 20393946Free PMC Article
Research on religion, spirituality, and mental health: a review.
Koenig HG
Can J Psychiatry 2009 May;54(5):283-91. doi: 10.1177/070674370905400502. PMID: 19497160
Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis.
UK ECT Review Group
Lancet 2003 Mar 8;361(9360):799-808. doi: 10.1016/S0140-6736(03)12705-5. PMID: 12642045

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...