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Anxiety disorder

MedGen UID:
361
Concept ID:
C0003469
Mental or Behavioral Dysfunction
Synonyms: Anxiety Disorder; Anxiety Disorders; Disorder, Anxiety; Disorders, Anxiety
SNOMED CT: Anxiety disorder (197480006)
 
Monarch Initiative: MONDO:0005618

Definition

A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [from NCI]

Professional guidelines

PubMed

Goodwin GM, Stein DJ
Adv Ther 2021 Sep;38(Suppl 2):45-51. Epub 2021 Aug 21 doi: 10.1007/s12325-021-01859-8. PMID: 34417991Free PMC Article
Stewart DE, Vigod SN
Annu Rev Med 2019 Jan 27;70:183-196. doi: 10.1146/annurev-med-041217-011106. PMID: 30691372
Bandelow B, Michaelis S, Wedekind D
Dialogues Clin Neurosci 2017 Jun;19(2):93-107. doi: 10.31887/DCNS.2017.19.2/bbandelow. PMID: 28867934Free PMC Article

Curated

UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management

UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

Recent clinical studies

Etiology

Kowalchuk A, Gonzalez SJ, Zoorob RJ
Am Fam Physician 2022 Dec;106(6):657-664. PMID: 36521463
Leigh E, Clark DM
Clin Child Fam Psychol Rev 2018 Sep;21(3):388-414. doi: 10.1007/s10567-018-0258-5. PMID: 29654442Free PMC Article
Newman MG, Shin KE, Zuellig AR
J Affect Disord 2016 Dec;206:94-102. Epub 2016 Jul 5 doi: 10.1016/j.jad.2016.07.008. PMID: 27466747Free PMC Article
Dean E
Nurs Stand 2016 Jul 13;30(46):15. doi: 10.7748/ns.30.46.15.s17. PMID: 27406490
Stein MB, Stein DJ
Lancet 2008 Mar 29;371(9618):1115-25. doi: 10.1016/S0140-6736(08)60488-2. PMID: 18374843

Diagnosis

Szuhany KL, Simon NM
JAMA 2022 Dec 27;328(24):2431-2445. doi: 10.1001/jama.2022.22744. PMID: 36573969
Koyuncu A, Ayan T, Ince Guliyev E, Erbilgin S, Deveci E
Curr Psychiatry Rep 2022 Feb;24(2):129-140. Epub 2022 Jan 25 doi: 10.1007/s11920-022-01324-5. PMID: 35076887
Showraki M, Showraki T, Brown K
Psychiatr Q 2020 Sep;91(3):905-914. doi: 10.1007/s11126-020-09747-0. PMID: 32383134
Maron E, Nutt D
Dialogues Clin Neurosci 2017 Jun;19(2):147-158. doi: 10.31887/DCNS.2017.19.2/dnutt. PMID: 28867939Free PMC Article
Stein MB, Stein DJ
Lancet 2008 Mar 29;371(9618):1115-25. doi: 10.1016/S0140-6736(08)60488-2. PMID: 18374843

Therapy

James AC, Reardon T, Soler A, James G, Creswell C
Cochrane Database Syst Rev 2020 Nov 16;11(11):CD013162. doi: 10.1002/14651858.CD013162.pub2. PMID: 33196111Free PMC Article
Kaur Gill A, Bansal Y, Bhandari R, Kaur S, Kaur J, Singh R, Kuhad A, Kuhad A
Drugs Today (Barc) 2019 Jul;55(7):423-437. doi: 10.1358/dot.2019.55.7.2958474. PMID: 31347611
Slee A, Nazareth I, Bondaronek P, Liu Y, Cheng Z, Freemantle N
Lancet 2019 Feb 23;393(10173):768-777. Epub 2019 Jan 31 doi: 10.1016/S0140-6736(18)31793-8. PMID: 30712879
Carpenter JK, Andrews LA, Witcraft SM, Powers MB, Smits JAJ, Hofmann SG
Depress Anxiety 2018 Jun;35(6):502-514. Epub 2018 Feb 16 doi: 10.1002/da.22728. PMID: 29451967Free PMC Article
Lakhan SE, Vieira KF
Nutr J 2010 Oct 7;9:42. doi: 10.1186/1475-2891-9-42. PMID: 20929532Free PMC Article

Prognosis

Nordh M, Wahlund T, Jolstedt M, Sahlin H, Bjureberg J, Ahlen J, Lalouni M, Salomonsson S, Vigerland S, Lavner M, Öst LG, Lenhard F, Hesser H, Mataix-Cols D, Högström J, Serlachius E
JAMA Psychiatry 2021 Jul 1;78(7):705-713. doi: 10.1001/jamapsychiatry.2021.0469. PMID: 33978699Free PMC Article
Stewart DE, Vigod SN
Annu Rev Med 2019 Jan 27;70:183-196. doi: 10.1146/annurev-med-041217-011106. PMID: 30691372
Aben A, De Wilde L, Hollevoet N, Henriquez C, Vandeweerdt M, Ponnet K, Van Tongel A
J Shoulder Elbow Surg 2018 Mar;27(3):387-392. doi: 10.1016/j.jse.2017.11.033. PMID: 29433642
Anderson PL, Price M, Edwards SM, Obasaju MA, Schmertz SK, Zimand E, Calamaras MR
J Consult Clin Psychol 2013 Oct;81(5):751-60. Epub 2013 Jun 24 doi: 10.1037/a0033559. PMID: 23796315
Spitzer RL, Kroenke K, Williams JB, Löwe B
Arch Intern Med 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092. PMID: 16717171

Clinical prediction guides

Mossman SA, Luft MJ, Schroeder HK, Varney ST, Fleck DE, Barzman DH, Gilman R, DelBello MP, Strawn JR
Ann Clin Psychiatry 2017 Nov;29(4):227-234A. PMID: 29069107Free PMC Article
Plummer F, Manea L, Trepel D, McMillan D
Gen Hosp Psychiatry 2016 Mar-Apr;39:24-31. Epub 2015 Nov 18 doi: 10.1016/j.genhosppsych.2015.11.005. PMID: 26719105
Matza LS, Morlock R, Sexton C, Malley K, Feltner D
Int J Methods Psychiatr Res 2010 Dec;19(4):223-32. Epub 2010 Aug 18 doi: 10.1002/mpr.323. PMID: 20718076Free PMC Article
Eisenberg D, Gollust SE, Golberstein E, Hefner JL
Am J Orthopsychiatry 2007 Oct;77(4):534-42. doi: 10.1037/0002-9432.77.4.534. PMID: 18194033
Connor KM, Davidson JR
Depress Anxiety 2003;18(2):76-82. doi: 10.1002/da.10113. PMID: 12964174

Recent systematic reviews

Zhang W, Yan Y, Wu Y, Yang H, Zhu P, Yan F, Zhao R, Tian P, Wang T, Fan Q, Su Z
Pharmacol Res 2022 May;179:106204. Epub 2022 Apr 1 doi: 10.1016/j.phrs.2022.106204. PMID: 35378276
Simpson CA, Diaz-Arteche C, Eliby D, Schwartz OS, Simmons JG, Cowan CSM
Clin Psychol Rev 2021 Feb;83:101943. Epub 2020 Oct 29 doi: 10.1016/j.cpr.2020.101943. PMID: 33271426
Slee A, Nazareth I, Bondaronek P, Liu Y, Cheng Z, Freemantle N
Lancet 2019 Feb 23;393(10173):768-777. Epub 2019 Jan 31 doi: 10.1016/S0140-6736(18)31793-8. PMID: 30712879
Whiting PF, Wolff RF, Deshpande S, Di Nisio M, Duffy S, Hernandez AV, Keurentjes JC, Lang S, Misso K, Ryder S, Schmidlkofer S, Westwood M, Kleijnen J
JAMA 2015 Jun 23-30;313(24):2456-73. doi: 10.1001/jama.2015.6358. PMID: 26103030
Stonerock GL, Hoffman BM, Smith PJ, Blumenthal JA
Ann Behav Med 2015 Aug;49(4):542-56. doi: 10.1007/s12160-014-9685-9. PMID: 25697132Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management
    • NICE, 2020
      UK NICE Clinical Guideline CG192, Antenatal and postnatal mental health: clinical management and service guidance, 2020

    Consumer resources

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