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Elevated circulating vitamin B12 concentration

MedGen UID:
1052593
Concept ID:
CN376531
Finding
Synonyms: Elevated plasma vitamin B12 level; Elevated serum cobalamin level; Elevated serum vitamin B12 level
 
HPO: HP:6000016

Definition

Concentration of vitamin B12 in the blood circulation above the upper limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated circulating vitamin B12 concentration

Professional guidelines

PubMed

Wild J , Shanmuganathan M , Hayashi M , Potter M , Britz-McKibbin P
Analyst 2019 Nov 4;144(22):6595-6608. doi: 10.1039/c9an01642b. PMID: 31608347
Nexo E, Hoffmann-Lücke E
Am J Clin Nutr 2011 Jul;94(1):359S-365S. Epub 2011 May 18 doi: 10.3945/ajcn.111.013458. PMID: 21593496Free PMC Article

Recent clinical studies

Etiology

Hannibal L, Jacobsen DW
Vitam Horm 2022;119:275-298. Epub 2022 Mar 15 doi: 10.1016/bs.vh.2022.02.001. PMID: 35337623
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
van Guldener C, Robinson K
Semin Thromb Hemost 2000;26(3):313-24. doi: 10.1055/s-2000-8407. PMID: 11011849
Mayer EL, Jacobsen DW, Robinson K
J Am Coll Cardiol 1996 Mar 1;27(3):517-27. doi: 10.1016/0735-1097(95)00508-0. PMID: 8606260

Diagnosis

Lacombe V, Lenaers G, Urbanski G
Nutrients 2022 May 14;14(10) doi: 10.3390/nu14102058. PMID: 35631199Free PMC Article
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
Nexo E, Hoffmann-Lücke E
Am J Clin Nutr 2011 Jul;94(1):359S-365S. Epub 2011 May 18 doi: 10.3945/ajcn.111.013458. PMID: 21593496Free PMC Article
Ermens AA, Vlasveld LT, Lindemans J
Clin Biochem 2003 Nov;36(8):585-90. doi: 10.1016/j.clinbiochem.2003.08.004. PMID: 14636871

Therapy

Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Sonmez Ozkarakaya I, Celik B, Karakukcu C, Altuner Torun Y
J Trace Elem Med Biol 2021 May;65:126724. Epub 2021 Jan 23 doi: 10.1016/j.jtemb.2021.126724. PMID: 33550037
van Guldener C, Robinson K
Semin Thromb Hemost 2000;26(3):313-24. doi: 10.1055/s-2000-8407. PMID: 11011849
Mayer EL, Jacobsen DW, Robinson K
J Am Coll Cardiol 1996 Mar 1;27(3):517-27. doi: 10.1016/0735-1097(95)00508-0. PMID: 8606260
Herbert V
Am J Clin Nutr 1994 May;59(5 Suppl):1213S-1222S. doi: 10.1093/ajcn/59.5.1213S. PMID: 8172125

Prognosis

Lacombe V, Lenaers G, Urbanski G
Nutrients 2022 May 14;14(10) doi: 10.3390/nu14102058. PMID: 35631199Free PMC Article
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Yamaguchi Y, Zampino M, Tanaka T, Bandinelli S, Osawa Y, Ferrucci L, Semba RD
J Gerontol A Biol Sci Med Sci 2021 Jun 14;76(7):1192-1197. doi: 10.1093/gerona/glaa324. PMID: 33367500Free PMC Article
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
van Guldener C, Robinson K
Semin Thromb Hemost 2000;26(3):313-24. doi: 10.1055/s-2000-8407. PMID: 11011849

Clinical prediction guides

Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Yamaguchi Y, Zampino M, Tanaka T, Bandinelli S, Osawa Y, Ferrucci L, Semba RD
J Gerontol A Biol Sci Med Sci 2021 Jun 14;76(7):1192-1197. doi: 10.1093/gerona/glaa324. PMID: 33367500Free PMC Article
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
de Lau LM, Smith AD, Refsum H, Johnston C, Breteler MM
J Neurol Neurosurg Psychiatry 2009 Feb;80(2):149-57. Epub 2008 Oct 31 doi: 10.1136/jnnp.2008.149286. PMID: 18977824
Ermens AA, Vlasveld LT, Lindemans J
Clin Biochem 2003 Nov;36(8):585-90. doi: 10.1016/j.clinbiochem.2003.08.004. PMID: 14636871

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