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Elevated urinary indoleacetic acid level

MedGen UID:
1052629
Concept ID:
CN377141
Finding
HPO: HP:6000332

Definition

The amount of indoleacetic acid in the urine, normalized for urine concentration, is above the upper limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated urinary indoleacetic acid level

Conditions with this feature

Neutral 1 amino acid transport defect
MedGen UID:
6723
Concept ID:
C0018609
Disease or Syndrome
Hartnup disorder (HND) is characterized by transient manifestations of pellagra, cerebellar ataxia, and psychosis. It is caused by impaired transport of neutral amino acids across epithelial cells in renal proximal tubules and intestinal mucosa (summary by Kleta et al., 2004).

Recent clinical studies

Etiology

Sen Gupta P, Grozinsky-Glasberg S, Drake WM, Akker SA, Perry L, Grossman AB, Druce MR
Clin Endocrinol (Oxf) 2014 Feb;80(2):246-52. Epub 2013 Jul 29 doi: 10.1111/cen.12270. PMID: 23790044

Diagnosis

Sen Gupta P, Grozinsky-Glasberg S, Drake WM, Akker SA, Perry L, Grossman AB, Druce MR
Clin Endocrinol (Oxf) 2014 Feb;80(2):246-52. Epub 2013 Jul 29 doi: 10.1111/cen.12270. PMID: 23790044

Prognosis

Sen Gupta P, Grozinsky-Glasberg S, Drake WM, Akker SA, Perry L, Grossman AB, Druce MR
Clin Endocrinol (Oxf) 2014 Feb;80(2):246-52. Epub 2013 Jul 29 doi: 10.1111/cen.12270. PMID: 23790044

Clinical prediction guides

Sen Gupta P, Grozinsky-Glasberg S, Drake WM, Akker SA, Perry L, Grossman AB, Druce MR
Clin Endocrinol (Oxf) 2014 Feb;80(2):246-52. Epub 2013 Jul 29 doi: 10.1111/cen.12270. PMID: 23790044
Hagan RL, Helander A
Aviat Space Environ Med 1997 Jan;68(1):30-4. PMID: 9006879
Yoshida K, Hirayama C
Tohoku J Exp Med 1984 Jan;142(1):35-41. doi: 10.1620/tjem.142.35. PMID: 6202023

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