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Leukemogenesis

MedGen UID:
109335
Concept ID:
C0598766
Neoplastic Process
Synonyms: Leukemogenesis/Lymphomagenesis; Lymphomagenesis

Definition

The causation (or induction), development, and progression of a leukaemic disease. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeukemogenesis

Professional guidelines

PubMed

Yabushita T, Chinen T, Nishiyama A, Asada S, Shimura R, Isobe T, Yamamoto K, Sato N, Enomoto Y, Tanaka Y, Fukuyama T, Satoh H, Kato K, Saitoh K, Ishikawa T, Soga T, Nannya Y, Fukagawa T, Nakanishi M, Kitagawa D, Kitamura T, Goyama S
Cell Rep 2023 Sep 26;42(9):113098. Epub 2023 Sep 14 doi: 10.1016/j.celrep.2023.113098. PMID: 37714156
Yin H, Wang J, Tan Y, Jiang M, Zhang H, Meng G
Trends Cancer 2023 Oct;9(10):855-870. Epub 2023 Jul 3 doi: 10.1016/j.trecan.2023.06.004. PMID: 37407363
Lamy T, Moignet A, Loughran TP Jr
Blood 2017 Mar 2;129(9):1082-1094. Epub 2017 Jan 23 doi: 10.1182/blood-2016-08-692590. PMID: 28115367

Recent clinical studies

Etiology

Makishima H, Bowman TV, Godley LA
Blood 2023 Mar 30;141(13):1544-1552. doi: 10.1182/blood.2022017715. PMID: 36455200Free PMC Article
Ediriwickrema A, Gentles AJ, Majeti R
Blood 2023 Jan 26;141(4):345-355. doi: 10.1182/blood.2021014670. PMID: 35926108Free PMC Article
Newell LF, Cook RJ
BMJ 2021 Oct 6;375:n2026. doi: 10.1136/bmj.n2026. PMID: 34615640
DeAngelo DJ, Jabbour E, Advani A
Am Soc Clin Oncol Educ Book 2020 May;40:330-342. doi: 10.1200/EDBK_280175. PMID: 32421447
Bullinger L, Döhner K, Döhner H
J Clin Oncol 2017 Mar 20;35(9):934-946. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.71.2208. PMID: 28297624

Diagnosis

Largeaud L, Collin M, Monselet N, Vergez F, Fregona V, Larcher L, Hirsch P, Duployez N, Bidet A, Luquet I, Bustamante J, Dufrechou S, Prade N, Nolla M, Hamelle C, Tavitian S, Habib C, Meynier M, Bellanne-Chantelot C, Donadieu J, De Fontbrune FS, Fieschi C, Ferster A, Delhommeau F, Delabesse E, Pasquet M
Haematologica 2023 Jun 1;108(6):1515-1529. doi: 10.3324/haematol.2022.282250. PMID: 36727400Free PMC Article
Semenzato G, Teramo A, Calabretto G, Gasparini VR, Zambello R
Leukemia 2022 Nov;36(11):2551-2557. Epub 2022 Sep 15 doi: 10.1038/s41375-022-01695-x. PMID: 36109593
Newell LF, Cook RJ
BMJ 2021 Oct 6;375:n2026. doi: 10.1136/bmj.n2026. PMID: 34615640
Iacobucci I, Mullighan CG
J Clin Oncol 2017 Mar 20;35(9):975-983. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.70.7836. PMID: 28297628Free PMC Article
Bullinger L, Döhner K, Döhner H
J Clin Oncol 2017 Mar 20;35(9):934-946. Epub 2017 Feb 13 doi: 10.1200/JCO.2016.71.2208. PMID: 28297624

Therapy

Newell LF, Cook RJ
BMJ 2021 Oct 6;375:n2026. doi: 10.1136/bmj.n2026. PMID: 34615640
Katoh M, Katoh M
Int J Mol Med 2020 Feb;45(2):279-297. Epub 2019 Dec 4 doi: 10.3892/ijmm.2019.4418. PMID: 31894255Free PMC Article
Metzeler KH, Herold T, Rothenberg-Thurley M, Amler S, Sauerland MC, Görlich D, Schneider S, Konstandin NP, Dufour A, Bräundl K, Ksienzyk B, Zellmeier E, Hartmann L, Greif PA, Fiegl M, Subklewe M, Bohlander SK, Krug U, Faldum A, Berdel WE, Wörmann B, Büchner T, Hiddemann W, Braess J, Spiekermann K; AMLCG Study Group
Blood 2016 Aug 4;128(5):686-98. Epub 2016 Jun 10 doi: 10.1182/blood-2016-01-693879. PMID: 27288520
Landau DA, Tausch E, Taylor-Weiner AN, Stewart C, Reiter JG, Bahlo J, Kluth S, Bozic I, Lawrence M, Böttcher S, Carter SL, Cibulskis K, Mertens D, Sougnez CL, Rosenberg M, Hess JM, Edelmann J, Kless S, Kneba M, Ritgen M, Fink A, Fischer K, Gabriel S, Lander ES, Nowak MA, Döhner H, Hallek M, Neuberg D, Getz G, Stilgenbauer S, Wu CJ
Nature 2015 Oct 22;526(7574):525-30. Epub 2015 Oct 14 doi: 10.1038/nature15395. PMID: 26466571Free PMC Article
Lindsley RC, Mar BG, Mazzola E, Grauman PV, Shareef S, Allen SL, Pigneux A, Wetzler M, Stuart RK, Erba HP, Damon LE, Powell BL, Lindeman N, Steensma DP, Wadleigh M, DeAngelo DJ, Neuberg D, Stone RM, Ebert BL
Blood 2015 Feb 26;125(9):1367-76. Epub 2014 Dec 30 doi: 10.1182/blood-2014-11-610543. PMID: 25550361Free PMC Article

Prognosis

Wu B, Chen X, Pan X, Deng X, Li S, Wang Z, Wang J, Liao D, Xu J, Chen M, Zhao C, Xue Z, Wang Y, Niu T, Lin J, Chen L, Liu Y, Chen C
PLoS Biol 2023 May;21(5):e3002088. Epub 2023 May 2 doi: 10.1371/journal.pbio.3002088. PMID: 37130348Free PMC Article
Cieśla M, Ngoc PCT, Muthukumar S, Todisco G, Madej M, Fritz H, Dimitriou M, Incarnato D, Hellström-Lindberg E, Bellodi C
Mol Cell 2023 Apr 6;83(7):1165-1179.e11. Epub 2023 Mar 20 doi: 10.1016/j.molcel.2023.02.024. PMID: 36944332
Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L
Cell Res 2022 Dec;32(12):1105-1123. Epub 2022 Oct 27 doi: 10.1038/s41422-022-00735-6. PMID: 36302855Free PMC Article
Metzeler KH, Herold T, Rothenberg-Thurley M, Amler S, Sauerland MC, Görlich D, Schneider S, Konstandin NP, Dufour A, Bräundl K, Ksienzyk B, Zellmeier E, Hartmann L, Greif PA, Fiegl M, Subklewe M, Bohlander SK, Krug U, Faldum A, Berdel WE, Wörmann B, Büchner T, Hiddemann W, Braess J, Spiekermann K; AMLCG Study Group
Blood 2016 Aug 4;128(5):686-98. Epub 2016 Jun 10 doi: 10.1182/blood-2016-01-693879. PMID: 27288520
Lindsley RC, Mar BG, Mazzola E, Grauman PV, Shareef S, Allen SL, Pigneux A, Wetzler M, Stuart RK, Erba HP, Damon LE, Powell BL, Lindeman N, Steensma DP, Wadleigh M, DeAngelo DJ, Neuberg D, Stone RM, Ebert BL
Blood 2015 Feb 26;125(9):1367-76. Epub 2014 Dec 30 doi: 10.1182/blood-2014-11-610543. PMID: 25550361Free PMC Article

Clinical prediction guides

Hu CL, Chen BY, Li Z, Yang T, Xu CH, Yang R, Yu PC, Zhao J, Liu T, Liu N, Shan B, Zhang Q, Song J, Fei MY, Zong LJ, Zhang JY, Wu JC, Chen SB, Wang Y, Chang B, Hou D, Liu P, Jiang Y, Li X, Chen X, Deng CH, Ren YY, Wang R, Jin J, Xue K, Zhang Y, Du M, Shi J, Wu LY, Chang CK, Shen S, Chen Z, Chen SJ, Liu X, Sun XJ, Zheng M, Wang L
Cell Res 2022 Dec;32(12):1105-1123. Epub 2022 Oct 27 doi: 10.1038/s41422-022-00735-6. PMID: 36302855Free PMC Article
Michmerhuizen NL, Klco JM, Mullighan CG
Blood 2020 Nov 12;136(20):2275-2289. doi: 10.1182/blood.2020007093. PMID: 32766874Free PMC Article
Nepstad I, Hatfield KJ, Grønningsæter IS, Reikvam H
Int J Mol Sci 2020 Apr 21;21(8) doi: 10.3390/ijms21082907. PMID: 32326335Free PMC Article
Chopra M, Bohlander SK
Genes Chromosomes Cancer 2019 Dec;58(12):850-858. Epub 2019 Aug 31 doi: 10.1002/gcc.22805. PMID: 31471945
Haas S, Trumpp A, Milsom MD
Cell Stem Cell 2018 May 3;22(5):627-638. doi: 10.1016/j.stem.2018.04.003. PMID: 29727678

Recent systematic reviews

Pezeshki A, Podder S, Kamel R, Corey SJ
Pediatr Blood Cancer 2017 Dec;64(12) Epub 2017 Jul 14 doi: 10.1002/pbc.26714. PMID: 28708320Free PMC Article
Karalexi MA, Dessypris N, Thomopoulos TP, Ntouvelis E, Kantzanou M, Diamantaras AA, Moschovi M, Baka M, Hatzipantelis E, Kourti M, Polychronopoulou S, Stiakaki E, Mora AM, Wunsch-Filho V, Infante-Rivard C, Loutradis D, Petridou ET
Eur J Cancer Prev 2017 Sep;26(5):433-441. doi: 10.1097/CEJ.0000000000000350. PMID: 28379884
Dessypris N, Karalexi MA, Ntouvelis E, Diamantaras AA, Papadakis V, Baka M, Hatzipantelis E, Kourti M, Moschovi M, Polychronopoulou S, Sidi V, Stiakaki E, Petridou ET
Cancer Epidemiol 2017 Apr;47:64-75. Epub 2017 Jan 25 doi: 10.1016/j.canep.2017.01.003. PMID: 28130996
Kupsa T, Horacek JM, Jebavy L
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2012 Dec;156(4):291-301. Epub 2012 Dec 7 doi: 10.5507/bp.2012.108. PMID: 23223353
Ye Z, Song H
Eur J Cancer 2005 May;41(7):980-9. doi: 10.1016/j.ejca.2005.01.014. PMID: 15862746

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