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Carcinogenesis

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
Synonyms: Carcinogeneses; Oncogeneses; Oncogenesis; Tumorigeneses; Tumorigenesis

Definition

A pathological process in which normal cells are transformed into malignant cancer cells within a primary tumor. [from NCI]

Professional guidelines

PubMed

Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Hakenberg OW, Dräger DL, Erbersdobler A, Naumann CM, Jünemann KP, Protzel C
Dtsch Arztebl Int 2018 Sep 28;115(39):646-652. doi: 10.3238/arztebl.2018.0646. PMID: 30375327Free PMC Article
Sofen B, Prado G, Emer J
Skin Therapy Lett 2016 Jan;21(1):1-7. PMID: 27224897

Recent clinical studies

Etiology

Ruze R, Song J, Yin X, Chen Y, Xu R, Wang C, Zhao Y
Signal Transduct Target Ther 2023 Mar 24;8(1):139. doi: 10.1038/s41392-023-01376-w. PMID: 36964133Free PMC Article
Karpiński TM, Ożarowski M, Stasiewicz M
Semin Cancer Biol 2022 Nov;86(Pt 3):420-430. Epub 2022 Jan 25 doi: 10.1016/j.semcancer.2022.01.004. PMID: 35090978
Rumgay H, Murphy N, Ferrari P, Soerjomataram I
Nutrients 2021 Sep 11;13(9) doi: 10.3390/nu13093173. PMID: 34579050Free PMC Article
Kontomanolis EN, Koutras A, Syllaios A, Schizas D, Mastoraki A, Garmpis N, Diakosavvas M, Angelou K, Tsatsaris G, Pagkalos A, Ntounis T, Fasoulakis Z
Anticancer Res 2020 Nov;40(11):6009-6015. doi: 10.21873/anticanres.14622. PMID: 33109539
Anderson NM, Simon MC
Curr Biol 2020 Aug 17;30(16):R921-R925. doi: 10.1016/j.cub.2020.06.081. PMID: 32810447Free PMC Article

Diagnosis

Wang Z, Dan W, Zhang N, Fang J, Yang Y
Gut Microbes 2023 Jan-Dec;15(1):2236364. doi: 10.1080/19490976.2023.2236364. PMID: 37482657Free PMC Article
Stasiewicz M, Karpiński TM
Semin Cancer Biol 2022 Nov;86(Pt 3):633-642. Epub 2021 Nov 4 doi: 10.1016/j.semcancer.2021.11.002. PMID: 34743032
Volkova LV, Pashov AI, Omelchuk NN
Int J Mol Sci 2021 Nov 22;22(22) doi: 10.3390/ijms222212571. PMID: 34830452Free PMC Article
N Kontomanolis E, Koutras A, Syllaios A, Schizas D, Kalagasidou S, Pagkalos A, Alatzidou D, Kantari P, Ntounis T, Fasoulakis Z
J BUON 2021 Sep-Oct;26(5):1723-1734. PMID: 34761575
Garrett WS
Science 2015 Apr 3;348(6230):80-6. doi: 10.1126/science.aaa4972. PMID: 25838377Free PMC Article

Therapy

Eyre TA, Shah NN, Dreyling M, Jurczak W, Wang Y, Cheah CY, Song Y, Gandhi M, Chay C, Sharman J, Andorsky DJ, Messersmith HM, Ruppert AS, Muthig VA, Ito R, Wang ML
Future Oncol 2022 Nov;18(36):3961-3969. Epub 2022 Nov 15 doi: 10.2217/fon-2022-0976. PMID: 36377973
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network
Cell 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. PMID: 33667368Free PMC Article
Tsimberidou AM, Fountzilas E, Nikanjam M, Kurzrock R
Cancer Treat Rev 2020 Jun;86:102019. Epub 2020 Mar 31 doi: 10.1016/j.ctrv.2020.102019. PMID: 32251926Free PMC Article
Sunami Y, Kleeff J
Prog Mol Biol Transl Sci 2019;164:189-216. Epub 2019 Mar 22 doi: 10.1016/bs.pmbts.2019.03.006. PMID: 31383405
Cheng X, Xu X, Chen D, Zhao F, Wang W
Biomed Pharmacother 2019 Feb;110:473-481. Epub 2018 Dec 6 doi: 10.1016/j.biopha.2018.11.082. PMID: 30530050

Prognosis

Murphy CC, Zaki TA
Nat Rev Gastroenterol Hepatol 2024 Jan;21(1):25-34. Epub 2023 Sep 18 doi: 10.1038/s41575-023-00841-9. PMID: 37723270
Wang Y, Yan Q, Fan C, Mo Y, Wang Y, Li X, Liao Q, Guo C, Li G, Zeng Z, Xiong W, Huang H
Sci China Life Sci 2023 Nov;66(11):2515-2526. Epub 2023 Apr 13 doi: 10.1007/s11427-022-2240-6. PMID: 37071289Free PMC Article
Willenbrink TJ, Ruiz ES, Cornejo CM, Schmults CD, Arron ST, Jambusaria-Pahlajani A
J Am Acad Dermatol 2020 Sep;83(3):709-717. Epub 2020 May 7 doi: 10.1016/j.jaad.2020.03.126. PMID: 32387665
Petryszyn P, Chapelle N, Matysiak-Budnik T
Dig Dis 2020;38(4):280-285. Epub 2020 Feb 17 doi: 10.1159/000506509. PMID: 32062657
Wu C, Li M, Meng H, Liu Y, Niu W, Zhou Y, Zhao R, Duan Y, Zeng Z, Li X, Li G, Xiong W, Zhou M
Sci China Life Sci 2019 May;62(5):640-647. Epub 2019 Mar 12 doi: 10.1007/s11427-018-9461-5. PMID: 30900169

Clinical prediction guides

Revsine M, Wang L, Forgues M, Behrens S, Craig AJ, Liu M, Tran B, Kelly M, Budhu A, Monge C, Xie C, Hernandez JM, Greten TF, Wang XW, Ma L
Cell Rep Med 2024 Feb 20;5(2):101394. Epub 2024 Jan 26 doi: 10.1016/j.xcrm.2024.101394. PMID: 38280378Free PMC Article
Ding GY, Ma JQ, Yun JP, Chen X, Ling Y, Zhang S, Shi JY, Chang YQ, Ji Y, Wang XY, Tan WM, Yuan KF, Yan B, Zhang XM, Liang F, Zhou J, Fan J, Zeng Y, Cai MY, Gao Q
J Hepatol 2022 Mar;76(3):608-618. Epub 2021 Nov 15 doi: 10.1016/j.jhep.2021.10.030. PMID: 34793865
Bell PD, Anderson JC, Srivastava A
Am J Surg Pathol 2022 Jan 1;46(1):e64-e70. doi: 10.1097/PAS.0000000000001806. PMID: 34545859
Zheng Q, Min S, Zhou Q
Biosci Rep 2021 Jun 25;41(6) doi: 10.1042/BSR20204370. PMID: 34017995Free PMC Article
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Recent systematic reviews

Luo D, Mei B, Wang P, Li X, Chen X, Wei G, Kuang F, Li B, Su S
Clin Microbiol Infect 2024 Mar;30(3):328-335. Epub 2023 Oct 20 doi: 10.1016/j.cmi.2023.10.016. PMID: 37866679
Ruze R, Song J, Yin X, Chen Y, Xu R, Wang C, Zhao Y
Signal Transduct Target Ther 2023 Mar 24;8(1):139. doi: 10.1038/s41392-023-01376-w. PMID: 36964133Free PMC Article
Li Y, Fan Z, Meng Y, Liu S, Zhan H
Biochim Biophys Acta Mol Basis Dis 2023 Jan 1;1869(1):166583. Epub 2022 Oct 18 doi: 10.1016/j.bbadis.2022.166583. PMID: 36270476
Zhang Y, Qian J, Gu C, Yang Y
Signal Transduct Target Ther 2021 Feb 24;6(1):78. doi: 10.1038/s41392-021-00486-7. PMID: 33623018Free PMC Article
Koliopoulos G, Nyaga VN, Santesso N, Bryant A, Martin-Hirsch PP, Mustafa RA, Schünemann H, Paraskevaidis E, Arbyn M
Cochrane Database Syst Rev 2017 Aug 10;8(8):CD008587. doi: 10.1002/14651858.CD008587.pub2. PMID: 28796882Free PMC Article

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    Practice guidelines

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    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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