U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lateral sinus thrombosis

MedGen UID:
124359
•Concept ID:
C0270639
•
Disease or Syndrome
Synonyms: Lateral Sinus Thromboses; Lateral Sinus Thrombosis; Sinus Thromboses, Transverse; Thromboses, Lateral Sinus; Thromboses, Transverse Sinus; Thrombosis, Lateral Sinus; Thrombosis, Transverse Sinus; Transverse Sinus Thromboses; Transverse Sinus Thrombosis
SNOMED CT: Cerebral venous thrombosis of lateral sinus (21258007); Thrombosis transverse sinus (192761004); Thrombosis of lateral venous sinus (21258007); Thrombosis of transverse sinus (21258007)
 
Monarch Initiative: MONDO:0002693

Definition

Formation or presence of a blood clot (thrombus) in the lateral sinuses. This condition is often associated with ear infections (otitis media or mastoiditis) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from craniocerebral trauma; brain neoplasms; neurosurgical procedures; thrombophilia; and other conditions. Clinical features include headache; vertigo; and increased intracranial pressure. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLateral sinus thrombosis

Professional guidelines

PubMed

Otogenic lateral sinus thrombosis in children: proposal of an experience-based treatment flowchart.
Scorpecci A, Massoud M, Giannantonio S, Zangari P, Lucidi D, Martines F, Foligno S, Di Felice G, Minozzi A, Luciani M, Marsella P
Eur Arch Otorhinolaryngol 2018 Aug;275(8):1971-1977. Epub 2018 Jun 8 doi: 10.1007/s00405-018-5033-1. PMID: 29948264
Management of paediatric otogenic cerebral venous sinus thrombosis: a systematic review.
Wong BY, Hickman S, Richards M, Jassar P, Wilson T
Clin Otolaryngol 2015 Dec;40(6):704-14. doi: 10.1111/coa.12504. PMID: 26769686
Paediatric otogenic lateral sinus thrombosis: therapeutic management, outcome and thrombophilic evaluation.
Novoa E, Podvinec M, Angst R, Gürtler N
Int J Pediatr Otorhinolaryngol 2013 Jun;77(6):996-1001. Epub 2013 Apr 29 doi: 10.1016/j.ijporl.2013.03.030. PMID: 23639339

Recent clinical studies

Etiology

Presentation and management of lateral sinus thrombosis following posterior fossa surgery.
Apra C, Kotbi O, Turc G, Corns R, Pagès M, Souillard-Scémama R, Dezamis E, Parraga E, Meder JF, Sauvageon X, Devaux B, Oppenheim C, Pallud J
J Neurosurg 2017 Jan;126(1):8-16. Epub 2016 Feb 26 doi: 10.3171/2015.11.JNS151881. PMID: 26918475
Otogenic lateral sinus thrombosis: case series and controversies.
Funamura JL, Nguyen AT, Diaz RC
Int J Pediatr Otorhinolaryngol 2014 May;78(5):866-70. Epub 2014 Mar 12 doi: 10.1016/j.ijporl.2014.03.002. PMID: 24680135
Paediatric otogenic lateral sinus thrombosis: therapeutic management, outcome and thrombophilic evaluation.
Novoa E, Podvinec M, Angst R, Gürtler N
Int J Pediatr Otorhinolaryngol 2013 Jun;77(6):996-1001. Epub 2013 Apr 29 doi: 10.1016/j.ijporl.2013.03.030. PMID: 23639339
Pediatric otogenic lateral sinus thrombosis: role of anticoagulation and surgery.
Sitton MS, Chun R
Int J Pediatr Otorhinolaryngol 2012 Mar;76(3):428-32. Epub 2012 Jan 25 doi: 10.1016/j.ijporl.2011.12.025. PMID: 22277267
Masked mastoiditis.
Holt GR, Gates GA
Laryngoscope 1983 Aug;93(8):1034-7. doi: 10.1288/00005537-198308000-00011. PMID: 6877011

Diagnosis

Lateral Sinus Thrombosis: The Importance of the Unaffected Sinus.
Glik A, Benkovich E, Kesler A, Ifergan G, Benifla M, Shelef I
J Neuroimaging 2016 Nov;26(6):599-604. Epub 2016 Feb 8 doi: 10.1111/jon.12336. PMID: 26853232
Otogenic lateral sinus thrombosis: case series and controversies.
Funamura JL, Nguyen AT, Diaz RC
Int J Pediatr Otorhinolaryngol 2014 May;78(5):866-70. Epub 2014 Mar 12 doi: 10.1016/j.ijporl.2014.03.002. PMID: 24680135
Management of otogenic lateral sinus thrombosis.
Singh GB, Rai AK, Singh S, Sahu R, Arora R
Auris Nasus Larynx 2014 Apr;41(2):143-7. Epub 2013 Nov 20 doi: 10.1016/j.anl.2013.10.005. PMID: 24268948
Pediatric otogenic lateral sinus thrombosis: role of anticoagulation and surgery.
Sitton MS, Chun R
Int J Pediatr Otorhinolaryngol 2012 Mar;76(3):428-32. Epub 2012 Jan 25 doi: 10.1016/j.ijporl.2011.12.025. PMID: 22277267
Masked mastoiditis.
Holt GR, Gates GA
Laryngoscope 1983 Aug;93(8):1034-7. doi: 10.1288/00005537-198308000-00011. PMID: 6877011

Therapy

Presentation and management of lateral sinus thrombosis following posterior fossa surgery.
Apra C, Kotbi O, Turc G, Corns R, Pagès M, Souillard-Scémama R, Dezamis E, Parraga E, Meder JF, Sauvageon X, Devaux B, Oppenheim C, Pallud J
J Neurosurg 2017 Jan;126(1):8-16. Epub 2016 Feb 26 doi: 10.3171/2015.11.JNS151881. PMID: 26918475
Otogenic lateral sinus thrombosis: case series and controversies.
Funamura JL, Nguyen AT, Diaz RC
Int J Pediatr Otorhinolaryngol 2014 May;78(5):866-70. Epub 2014 Mar 12 doi: 10.1016/j.ijporl.2014.03.002. PMID: 24680135
Paediatric otogenic lateral sinus thrombosis: therapeutic management, outcome and thrombophilic evaluation.
Novoa E, Podvinec M, Angst R, Gürtler N
Int J Pediatr Otorhinolaryngol 2013 Jun;77(6):996-1001. Epub 2013 Apr 29 doi: 10.1016/j.ijporl.2013.03.030. PMID: 23639339
Pediatric otogenic lateral sinus thrombosis: role of anticoagulation and surgery.
Sitton MS, Chun R
Int J Pediatr Otorhinolaryngol 2012 Mar;76(3):428-32. Epub 2012 Jan 25 doi: 10.1016/j.ijporl.2011.12.025. PMID: 22277267
Masked mastoiditis.
Holt GR, Gates GA
Laryngoscope 1983 Aug;93(8):1034-7. doi: 10.1288/00005537-198308000-00011. PMID: 6877011

Prognosis

Presentation and management of lateral sinus thrombosis following posterior fossa surgery.
Apra C, Kotbi O, Turc G, Corns R, Pagès M, Souillard-Scémama R, Dezamis E, Parraga E, Meder JF, Sauvageon X, Devaux B, Oppenheim C, Pallud J
J Neurosurg 2017 Jan;126(1):8-16. Epub 2016 Feb 26 doi: 10.3171/2015.11.JNS151881. PMID: 26918475
Otogenic lateral sinus thrombosis: case series and controversies.
Funamura JL, Nguyen AT, Diaz RC
Int J Pediatr Otorhinolaryngol 2014 May;78(5):866-70. Epub 2014 Mar 12 doi: 10.1016/j.ijporl.2014.03.002. PMID: 24680135
Management of otogenic lateral sinus thrombosis.
Singh GB, Rai AK, Singh S, Sahu R, Arora R
Auris Nasus Larynx 2014 Apr;41(2):143-7. Epub 2013 Nov 20 doi: 10.1016/j.anl.2013.10.005. PMID: 24268948
Paediatric otogenic lateral sinus thrombosis: therapeutic management, outcome and thrombophilic evaluation.
Novoa E, Podvinec M, Angst R, Gürtler N
Int J Pediatr Otorhinolaryngol 2013 Jun;77(6):996-1001. Epub 2013 Apr 29 doi: 10.1016/j.ijporl.2013.03.030. PMID: 23639339
Masked mastoiditis.
Holt GR, Gates GA
Laryngoscope 1983 Aug;93(8):1034-7. doi: 10.1288/00005537-198308000-00011. PMID: 6877011

Clinical prediction guides

Stenting of symptomatic lateral sinus thrombosis refractory to mechanical thrombectomy.
Lu G, Shin JH, Song Y, Lee DH
Interv Neuroradiol 2019 Dec;25(6):714-720. Epub 2019 May 27 doi: 10.1177/1591019919852168. PMID: 31132906Free PMC Article
Otogenic lateral sinus thrombosis in children: proposal of an experience-based treatment flowchart.
Scorpecci A, Massoud M, Giannantonio S, Zangari P, Lucidi D, Martines F, Foligno S, Di Felice G, Minozzi A, Luciani M, Marsella P
Eur Arch Otorhinolaryngol 2018 Aug;275(8):1971-1977. Epub 2018 Jun 8 doi: 10.1007/s00405-018-5033-1. PMID: 29948264
Management of paediatric otogenic cerebral venous sinus thrombosis: a systematic review.
Wong BY, Hickman S, Richards M, Jassar P, Wilson T
Clin Otolaryngol 2015 Dec;40(6):704-14. doi: 10.1111/coa.12504. PMID: 26769686
Management of otogenic lateral sinus thrombosis.
Singh GB, Rai AK, Singh S, Sahu R, Arora R
Auris Nasus Larynx 2014 Apr;41(2):143-7. Epub 2013 Nov 20 doi: 10.1016/j.anl.2013.10.005. PMID: 24268948
Otogenic lateral sinus thrombosis in children.
Bielecki I, Cofała M, Mierzwiński J
Otol Neurotol 2011 Sep;32(7):1111-5. doi: 10.1097/MAO.0b013e3182267eea. PMID: 21817945

Recent systematic reviews

Management of Acute Complicated Mastoiditis: A Systematic Review and Meta-analysis.
Kaufmann MR, Shetty K, Camilon PR, Shetty A, Levi JR, Devaiah AK
Pediatr Infect Dis J 2022 Apr 1;41(4):297-301. doi: 10.1097/INF.0000000000003452. PMID: 35175990
Management of paediatric otogenic cerebral venous sinus thrombosis: a systematic review.
Wong BY, Hickman S, Richards M, Jassar P, Wilson T
Clin Otolaryngol 2015 Dec;40(6):704-14. doi: 10.1111/coa.12504. PMID: 26769686

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...