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Intracranial Embolism and Thrombosis

MedGen UID:
40190
•Concept ID:
C0007781
•
Disease or Syndrome

Definition

Embolism or thrombosis involving blood vessels which supply intracranial structures. Emboli may originate from extracranial or intracranial sources. Thrombosis may occur in arterial or venous structures. [from MeSH]

Professional guidelines

PubMed

External validation of the ability of the DRAGON score to predict outcome after thrombolysis treatment.
Ovesen C, Christensen A, Nielsen JK, Christensen H
J Clin Neurosci 2013 Nov;20(11):1635-6. Epub 2013 Sep 11 doi: 10.1016/j.jocn.2013.04.023. PMID: 24035206

Recent clinical studies

Etiology

Cerebral microemboli and cognitive impairment.
Russell D
J Neurol Sci 2002 Nov 15;203-204:211-4. doi: 10.1016/s0022-510x(02)00293-9. PMID: 12417386
Thrombolytic therapy.
Brott T
Neurol Clin 1992 Feb;10(1):219-32. PMID: 1557004
Ticlopidine hydrochloride.
Blissitt PA
J Neurosci Nurs 1992 Oct;24(5):296-300. doi: 10.1097/01376517-199210000-00012. PMID: 1402156
Cardiac embolism: the neurologist's perspective.
Sherman DG
Am J Cardiol 1990 Feb 2;65(6):32C-37C. doi: 10.1016/0002-9149(90)90113-f. PMID: 2405625
Dural sinus and cerebral venous thrombosis.
Nagpal RD
Neurosurg Rev 1983;6(3):155-60. doi: 10.1007/BF01742767. PMID: 6371593

Diagnosis

Vertebrobasilar ischaemia.
Martin PJ
QJM 1998 Dec;91(12):799-811. doi: 10.1093/qjmed/91.12.799. PMID: 10024945
Vertebrobasilar thrombosis: diagnosis, management, and the use of intra-arterial thrombolytics.
Becker KJ, Purcell LL, Hacke W, Hanley DF
Crit Care Med 1996 Oct;24(10):1729-42. doi: 10.1097/00003246-199610000-00022. PMID: 8874314
Cerebral venous thrombosis.
Martin PJ, Enevoldson TP
Postgrad Med J 1996 Feb;72(844):72-6. doi: 10.1136/pgmj.72.844.72. PMID: 8871455Free PMC Article
Locked-in syndrome.
Sepcić J, Sepić-Grahovac D, Strenja-Grubesić J, Antonelli L, Andrasević D
Neurol Croat 1992;41(3):157-61. PMID: 1463800
Dural sinus and cerebral venous thrombosis.
Nagpal RD
Neurosurg Rev 1983;6(3):155-60. doi: 10.1007/BF01742767. PMID: 6371593

Therapy

Anticoagulant and defibrinogenating agents in acute ischemic stroke and cerebral venous thrombosis.
Meschia JF
Semin Neurol 1998;18(4):461-70. doi: 10.1055/s-2008-1040899. PMID: 9932617
Cerebral venous thrombosis.
Martin PJ, Enevoldson TP
Postgrad Med J 1996 Feb;72(844):72-6. doi: 10.1136/pgmj.72.844.72. PMID: 8871455Free PMC Article
Prophylaxis and acute therapy of arterial embolism with special reference to cerebral embolism.
Tettenborn B, Krämer G, Erbel R
Herz 1991 Dec;16(6):444-55. PMID: 1765348
Stroke therapy.
Zivin JA, Choi DW
Sci Am 1991 Jul;265(1):56-63. doi: 10.1038/scientificamerican0791-56. PMID: 1679258
Cerebral embolism.
Sherman DG, Dyken ML, Fisher M, Harrison MJ, Hart RG
Chest 1986 Feb;89(2 Suppl):82S-98S. doi: 10.1378/chest.89.2_supplement.82s. PMID: 3510833

Prognosis

Brain embolism, revisited.
Caplan LR
Neurology 1993 Jul;43(7):1281-7. doi: 10.1212/wnl.43.7.1281. PMID: 8327124
Cerebral venous thrombosis.
Ameri A, Bousser MG
Neurol Clin 1992 Feb;10(1):87-111. PMID: 1557011
Fibrinogen and mechanisms of thrombosis. A difficult link.
Di Minno G, Cerbone A, Margaglione M, Vecchione G, Grandone E, Mancini M
Eur J Epidemiol 1992 May;8 Suppl 1:88-91. doi: 10.1007/BF00145357. PMID: 1505658
ENDOCARDITIS.
FRIEDBERG CK
Bull N Y Acad Med 1964 Jul;40(7):522-31. PMID: 14150924Free PMC Article
ANTICOAGULANT THERAPY TODAY.
VIGRAN IM
Angiology 1964 Jan;15:1-10. doi: 10.1177/000331976401500101. PMID: 14106728

Clinical prediction guides

Distribution of Cardioembolic Stroke: A Cohort Study.
Pierik R, Algra A, van Dijk E, Erasmus ME, van Gelder IC, Koudstaal PJ, Luijckx GR, Nederkoorn PJ, van Oostenbrugge RJ, Ruigrok YM, Scheeren TWL, Uyttenboogaart M, Visser MC, Wermer MJH, van den Bergh WM; on behalf of the Parelsnoer Institute-Cerebrovascular Accident Study Group
Cerebrovasc Dis 2020;49(1):97-104. Epub 2020 Jan 21 doi: 10.1159/000505616. PMID: 31962331
Brain embolism, revisited.
Caplan LR
Neurology 1993 Jul;43(7):1281-7. doi: 10.1212/wnl.43.7.1281. PMID: 8327124
Fibrinogen and mechanisms of thrombosis. A difficult link.
Di Minno G, Cerbone A, Margaglione M, Vecchione G, Grandone E, Mancini M
Eur J Epidemiol 1992 May;8 Suppl 1:88-91. doi: 10.1007/BF00145357. PMID: 1505658
Locked-in syndrome.
Sepcić J, Sepić-Grahovac D, Strenja-Grubesić J, Antonelli L, Andrasević D
Neurol Croat 1992;41(3):157-61. PMID: 1463800
The cerebral venous system.
Schmidek HH, Auer LM, Kapp JP
Neurosurgery 1985 Oct;17(4):663-78. doi: 10.1227/00006123-198510000-00024. PMID: 3903542

Recent systematic reviews

Alcohol consumption and the risk of morbidity and mortality for different stroke types--a systematic review and meta-analysis.
Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, Rehm J
BMC Public Health 2010 May 18;10:258. doi: 10.1186/1471-2458-10-258. PMID: 20482788Free PMC Article
Correlation between carotid intraplaque hemorrhage and clinical symptoms: systematic review of observational studies.
Gao P, Chen ZQ, Bao YH, Jiao LQ, Ling F
Stroke 2007 Aug;38(8):2382-90. Epub 2007 Jun 28 doi: 10.1161/STROKEAHA.107.482760. PMID: 17600232

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