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Buccal mucosa neoplasm

MedGen UID:: 138021
•Concept ID:: C0345563
•: Neoplastic Process

Synonyms:	Buccal Mucosa Neoplasm; buccal mucosa neoplasm; buccal mucosa neoplasm (disease); Buccal Mucosa Tumor; buccal mucosa tumor; buccal mucosa tumour; Neoplasm of buccal mucosa; Neoplasm of Buccal Mucosa; neoplasm of buccal mucosa; Neoplasm of the Buccal Mucosa; neoplasm of the buccal mucosa; Tumor of buccal mucosa; Tumor of Buccal Mucosa; tumor of buccal mucosa; Tumor of cheek mucosa; Tumor of the Buccal Mucosa; tumor of the buccal mucosa; tumour of buccal mucosa; tumour of the buccal mucosa
SNOMED CT:	Neoplasm of buccal mucosa (126802007); Tumor of buccal mucosa (126802007); Tumor of cheek mucosa (126802007)

Monarch Initiative:	MONDO:0021241

Definition

A benign or malignant neoplasm that affects the buccal mucosa. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBuccal mucosa neoplasm

Disorder of digestive system
- Abnormality of the digestive system
  - Digestive system neoplasm
    - Neoplasm of the oral cavity
      - Buccal mucosa neoplasm
        Benign neoplasm of buccal mucosa
        Papilloma of buccal mucosa
        Cheek mucosa cancer
        Squamous cell carcinoma of buccal mucosa
        Buccal Mucosa Verrucous Carcinoma

Professional guidelines

PubMed

Management of oral potentially malignant disorders.

Kerr AR, Lodi G
Oral Dis 2021 Nov;27(8):2008-2025. Epub 2021 Oct 9 doi: 10.1111/odi.13980. PMID: 34324758

Pathogenesis and Treatment of Pancreatic Cancer Related Pain.

Lohse I, Brothers SP
Anticancer Res 2020 Apr;40(4):1789-1796. doi: 10.21873/anticanres.14133. PMID: 32234867 Free PMC Article

Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.

Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048

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Recent clinical studies

Etiology

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Lorenzo-Pouso AI, Lafuente-Ibáñez de Mendoza I, Pérez-Sayáns M, Pérez-Jardón A, Chamorro-Petronacci CM, Blanco-Carrión A, Aguirre-Urízar JM
J Oral Pathol Med 2022 Aug;51(7):585-593. Epub 2022 May 12 doi: 10.1111/jop.13304. PMID: 35488780 Free PMC Article

Nomogram predicting long-term overall and cancer-specific survival of patients with buccal mucosa cancer.

Wang F, Wen J, Cao S, Yang X, Yang Z, Li H, Meng H, Thieringer FM, Wei J
BMC Oral Health 2022 Apr 22;22(1):138. doi: 10.1186/s12903-022-02147-9. PMID: 35459139 Free PMC Article

Oral verruciform xanthoma in chronic graft-versus-host disease patients.

Bar O, Elad S, Avni B, Abu-Tair J, Zaharia B, Hanut A, Zadik Y
Support Care Cancer 2021 Jan;29(1):79-84. Epub 2020 Aug 15 doi: 10.1007/s00520-020-05681-w. PMID: 32803727

Squamous cell carcinoma of tongue and buccal mucosa: clinico-pathologically different entities.

Nair S, Singh B, Pawar PV, Datta S, Nair D, Kane S, Chaturvedi P
Eur Arch Otorhinolaryngol 2016 Nov;273(11):3921-3928. Epub 2016 Apr 20 doi: 10.1007/s00405-016-4051-0. PMID: 27098612

Oral mucositis.

Raber-Durlacher JE, Elad S, Barasch A
Oral Oncol 2010 Jun;46(6):452-6. Epub 2010 Apr 18 doi: 10.1016/j.oraloncology.2010.03.012. PMID: 20403721

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Diagnosis

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Oral verruciform xanthoma in chronic graft-versus-host disease patients.

Bar O, Elad S, Avni B, Abu-Tair J, Zaharia B, Hanut A, Zadik Y
Support Care Cancer 2021 Jan;29(1):79-84. Epub 2020 Aug 15 doi: 10.1007/s00520-020-05681-w. PMID: 32803727

Multifocal Epithelial Hyperplasia.

Agnew C, Alexander S, Prabhu N
J Dent Child (Chic) 2017 Jan 15;84(1):47-49. PMID: 28387191

Fentanyl Buccal Soluble Film: A Review in Breakthrough Cancer Pain.

Garnock-Jones KP
Clin Drug Investig 2016 May;36(5):413-9. doi: 10.1007/s40261-016-0394-y. PMID: 27007271

Betel chewer's mucosa--a review.

Reichart PA, Phillipsen HP
J Oral Pathol Med 1998 Jul;27(6):239-42. doi: 10.1111/j.1600-0714.1998.tb01949.x. PMID: 9707274

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Therapy

Yuwanati M, Gondivkar S, Sarode SC, Gadbail A, Desai A, Mhaske S, Pathak SK, N Khatib M
Future Oncol 2021 Mar;17(8):979-990. Epub 2021 Feb 5 doi: 10.2217/fon-2020-0881. PMID: 33541115

The Oral Microbiota May Have Influence on Oral Cancer.

Zhang L, Liu Y, Zheng HJ, Zhang CP
Front Cell Infect Microbiol 2019;9:476. Epub 2020 Jan 15 doi: 10.3389/fcimb.2019.00476. PMID: 32010645 Free PMC Article

Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy.

Driehuis E, Kolders S, Spelier S, Lõhmussaar K, Willems SM, Devriese LA, de Bree R, de Ruiter EJ, Korving J, Begthel H, van Es JH, Geurts V, He GW, van Jaarsveld RH, Oka R, Muraro MJ, Vivié J, Zandvliet MMJM, Hendrickx APA, Iakobachvili N, Sridevi P, Kranenburg O, van Boxtel R, Kops GJPL, Tuveson DA, Peters PJ, van Oudenaarden A, Clevers H
Cancer Discov 2019 Jul;9(7):852-871. Epub 2019 May 3 doi: 10.1158/2159-8290.CD-18-1522. PMID: 31053628

Randomized double-blind, placebo-controlled trial evaluating oral glutamine on radiation-induced oral mucositis and dermatitis in head and neck cancer patients.

Huang CJ, Huang MY, Fang PT, Chen F, Wang YT, Chen CH, Yuan SS, Huang CM, Luo KH, Chuang HY, Wang YY, Lee HH
Am J Clin Nutr 2019 Mar 1;109(3):606-614. doi: 10.1093/ajcn/nqy329. PMID: 30753262 Free PMC Article

Oral mucositis.

Raber-Durlacher JE, Elad S, Barasch A
Oral Oncol 2010 Jun;46(6):452-6. Epub 2010 Apr 18 doi: 10.1016/j.oraloncology.2010.03.012. PMID: 20403721

See all (1971)

Prognosis

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Nomogram predicting long-term overall and cancer-specific survival of patients with buccal mucosa cancer.

Wang F, Wen J, Cao S, Yang X, Yang Z, Li H, Meng H, Thieringer FM, Wei J
BMC Oral Health 2022 Apr 22;22(1):138. doi: 10.1186/s12903-022-02147-9. PMID: 35459139 Free PMC Article

Transcriptome profiling and pathway analysis in squamous cell carcinoma of buccal mucosa.

Patel KD, Vora HH, Trivedi TI, Patel JB, Pandya SJ, Jetly DH, Patel PS
Exp Mol Pathol 2020 Apr;113:104378. Epub 2020 Jan 11 doi: 10.1016/j.yexmp.2020.104378. PMID: 31930966

Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review.

Shrestha AD, Vedsted P, Kallestrup P, Neupane D
Eur J Cancer Care (Engl) 2020 Mar;29(2):e13207. Epub 2019 Dec 10 doi: 10.1111/ecc.13207. PMID: 31820851

Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.

Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, Maymone AC, Vashi NA
J Am Acad Dermatol 2019 Jul;81(1):59-71. Epub 2018 Nov 14 doi: 10.1016/j.jaad.2018.09.060. PMID: 30447325

See all (2329)

Clinical prediction guides

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Nomogram predicting long-term overall and cancer-specific survival of patients with buccal mucosa cancer.

Wang F, Wen J, Cao S, Yang X, Yang Z, Li H, Meng H, Thieringer FM, Wei J
BMC Oral Health 2022 Apr 22;22(1):138. doi: 10.1186/s12903-022-02147-9. PMID: 35459139 Free PMC Article

Oral submucous fibrosis: An enigmatic morpho-insight.

Hande AH, Chaudhary MS, Gawande MN, Gadbail AR, Zade PR, Bajaj S, Patil SK, Tekade S
J Cancer Res Ther 2019 Jul-Sep;15(3):463-469. doi: 10.4103/jcrt.JCRT_522_17. PMID: 31169205

Fentanyl Buccal Soluble Film: A Review in Breakthrough Cancer Pain.

Garnock-Jones KP
Clin Drug Investig 2016 May;36(5):413-9. doi: 10.1007/s40261-016-0394-y. PMID: 27007271

Clinical application of micronucleus test in exfoliated buccal cells: A systematic review and metanalysis.

Bolognesi C, Bonassi S, Knasmueller S, Fenech M, Bruzzone M, Lando C, Ceppi M
Mutat Res Rev Mutat Res 2015 Oct-Dec;766:20-31. Epub 2015 Aug 5 doi: 10.1016/j.mrrev.2015.07.002. PMID: 26596545

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Recent systematic reviews

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.

Oral Mucosal Melanoma.

Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749

Presence of SARS-CoV-2 and Its Entry Factors in Oral Tissues and Cells: A Systematic Review.

Salas Orozco MF, Niño-Martínez N, Martínez-Castañón GA, Patiño Marín N, Sámano Valencia C, Dipp Velázquez FA, Sosa Munguía PDC, Casillas Santana MA
Medicina (Kaunas) 2021 May 23;57(6) doi: 10.3390/medicina57060523. PMID: 34070998 Free PMC Article

Yuwanati M, Gondivkar S, Sarode SC, Gadbail A, Desai A, Mhaske S, Pathak SK, N Khatib M
Future Oncol 2021 Mar;17(8):979-990. Epub 2021 Feb 5 doi: 10.2217/fon-2020-0881. PMID: 33541115

Oral potentially malignant disorders: A comprehensive review on clinical aspects and management.

Warnakulasuriya S
Oral Oncol 2020 Mar;102:104550. Epub 2020 Jan 22 doi: 10.1016/j.oraloncology.2019.104550. PMID: 31981993

See all (76)

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Buccal mucosa neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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