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Neoplasm of the oral cavity

MedGen UID:
7722
•Concept ID:
C0026640
•
Neoplastic Process
Synonyms: Mouth neoplasm; Oral cavity neoplasm
SNOMED CT: Neoplasm of mouth (126797001); Tumor of oral cavity (235075007); Tumor of mouth (126797001)
 
HPO: HP:0100649
Monarch Initiative: MONDO:0021245

Definition

A tumor (abnormal growth of tissue) of the oral cavity. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of the oral cavity

Professional guidelines

PubMed

Treatment of oral squamous cell carcinoma using anti-HER2 immunonanoshells.
Fekrazad R, Hakimiha N, Farokhi E, Rasaee MJ, Ardestani MS, Kalhori KA, Sheikholeslami F
Int J Nanomedicine 2011;6:2749-55. Epub 2011 Nov 9 doi: 10.2147/IJN.S24548. PMID: 22131825Free PMC Article

Recent clinical studies

Etiology

Occult metastases of oral maxillary squamous cell carcinoma: Systematic review and meta-analysis.
de la Fuente C, Prat-Valero N, Alberola-Ferranti M, Mis-Castell D, Sáez-Barba M, Pujol-Pina R, Pamias-Romero J, Bescós-Atín C
Head Neck 2023 Mar;45(3):733-744. Epub 2022 Dec 14 doi: 10.1002/hed.27276. PMID: 36515647
Secretory Carcinoma of the Oral Cavity: A Retrospective Case Series with Review of Literature.
Venkat S, Fitzpatrick S, Drew PA, Bhattacharyya I, Cohen DM, Islam MN
Head Neck Pathol 2021 Sep;15(3):893-904. Epub 2021 Mar 3 doi: 10.1007/s12105-021-01310-y. PMID: 33660147Free PMC Article
Immunohistochemical analysis of osteopontin expression in oral squamous cell carcinoma.
Jeyasivanesan DL, Mohamed SP, Pandiar D, Basheer S
Indian J Dent Res 2019 Jul-Aug;30(4):539-543. doi: 10.4103/ijdr.IJDR_474_17. PMID: 31745049
Stereology study of oral verrucous carcinoma.
Liu O, Zhang H, Wang Y, Quan H, Zhang J, Zhou J, Zuo J, Tang J, Fang X, Wang W, Zhao L, Tang Z
J BUON 2012 Apr-Jun;17(2):343-9. PMID: 22740216
Gastroesophageal reflux as a possible co-promoting factor in the development of the squamous-cell carcinoma of the oral cavity, of the larynx and of the pharynx.
Mercante G, Bacciu A, Ferri T, Bacciu S
Acta Otorhinolaryngol Belg 2003;57(2):113-7. PMID: 12836467

Diagnosis

Secretory Carcinoma of the Oral Cavity: A Retrospective Case Series with Review of Literature.
Venkat S, Fitzpatrick S, Drew PA, Bhattacharyya I, Cohen DM, Islam MN
Head Neck Pathol 2021 Sep;15(3):893-904. Epub 2021 Mar 3 doi: 10.1007/s12105-021-01310-y. PMID: 33660147Free PMC Article
Solitary fibrous tumour of the oral cavity: An update.
Nunes FB, Sant'Ana MSP, Silva AMB, Agostini M, Silva Canedo NH, de Andrade BAB, Romañach MJ, Corrêa DL, Tomasi RA, Radhakrishnan R, Gomez RS, de Sousa SF, Brennan PA, Fonseca FP
J Oral Pathol Med 2020 Jan;49(1):14-20. Epub 2019 Sep 15 doi: 10.1111/jop.12953. PMID: 31424136
Immunohistochemical analysis of osteopontin expression in oral squamous cell carcinoma.
Jeyasivanesan DL, Mohamed SP, Pandiar D, Basheer S
Indian J Dent Res 2019 Jul-Aug;30(4):539-543. doi: 10.4103/ijdr.IJDR_474_17. PMID: 31745049
Histologic subtypes of oral squamous cell carcinoma: prognostic relevance.
Pereira MC, Oliveira DT, Landman G, Kowalski LP
J Can Dent Assoc 2007 May;73(4):339-44. PMID: 17484800
Delayed diagnosis of cancer with emphasis on oral cavity cancers.
Stoykova M
Folia Med (Plovdiv) 1999;41(1):132-5. PMID: 10462942

Therapy

Treatment of oral squamous cell carcinoma using anti-HER2 immunonanoshells.
Fekrazad R, Hakimiha N, Farokhi E, Rasaee MJ, Ardestani MS, Kalhori KA, Sheikholeslami F
Int J Nanomedicine 2011;6:2749-55. Epub 2011 Nov 9 doi: 10.2147/IJN.S24548. PMID: 22131825Free PMC Article

Prognosis

Bacterial alterations in salivary microbiota and their association in oral cancer.
Lee WH, Chen HM, Yang SF, Liang C, Peng CY, Lin FM, Tsai LL, Wu BC, Hsin CH, Chuang CY, Yang T, Yang TL, Ho SY, Chen WL, Ueng KC, Huang HD, Huang CN, Jong YJ
Sci Rep 2017 Nov 28;7(1):16540. doi: 10.1038/s41598-017-16418-x. PMID: 29184122Free PMC Article
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Suarez-Roa ML, Asbun-Bojalil J, Ruiz-Godoy LM, Meneses-García AA
Aust Dent J 2012 Sep;57(3):300-7. Epub 2012 Jun 28 doi: 10.1111/j.1834-7819.2012.01705.x. PMID: 22924352
Stereology study of oral verrucous carcinoma.
Liu O, Zhang H, Wang Y, Quan H, Zhang J, Zhou J, Zuo J, Tang J, Fang X, Wang W, Zhao L, Tang Z
J BUON 2012 Apr-Jun;17(2):343-9. PMID: 22740216
Surgical management of lip cancer.
Moretti A, Vitullo F, Augurio A, Pacella A, Croce A
Acta Otorhinolaryngol Ital 2011 Feb;31(1):5-10. PMID: 21808457Free PMC Article
Histologic subtypes of oral squamous cell carcinoma: prognostic relevance.
Pereira MC, Oliveira DT, Landman G, Kowalski LP
J Can Dent Assoc 2007 May;73(4):339-44. PMID: 17484800

Clinical prediction guides

Immunohistochemical analysis of osteopontin expression in oral squamous cell carcinoma.
Jeyasivanesan DL, Mohamed SP, Pandiar D, Basheer S
Indian J Dent Res 2019 Jul-Aug;30(4):539-543. doi: 10.4103/ijdr.IJDR_474_17. PMID: 31745049
Expression of Wilms' tumor 1 (WT1) in oral squamous cell carcinoma.
Mikami T, Hada T, Chosa N, Ishisaki A, Mizuki H, Takeda Y
J Oral Pathol Med 2013 Feb;42(2):133-9. Epub 2012 Jun 5 doi: 10.1111/j.1600-0714.2012.01182.x. PMID: 22672247
Immunoexpression of matrix metalloproteinases and their inhibitors in different areas of oral squamous cell carcinoma.
Suarez-Roa ML, Asbun-Bojalil J, Ruiz-Godoy LM, Meneses-García AA
Aust Dent J 2012 Sep;57(3):300-7. Epub 2012 Jun 28 doi: 10.1111/j.1834-7819.2012.01705.x. PMID: 22924352
Stereology study of oral verrucous carcinoma.
Liu O, Zhang H, Wang Y, Quan H, Zhang J, Zhou J, Zuo J, Tang J, Fang X, Wang W, Zhao L, Tang Z
J BUON 2012 Apr-Jun;17(2):343-9. PMID: 22740216
Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas.
Pimenta FJ, Gomes DA, Perdigão PF, Barbosa AA, Romano-Silva MA, Gomez MV, Aldaz CM, De Marco L, Gomez RS
Int J Cancer 2006 Mar 1;118(5):1154-8. doi: 10.1002/ijc.21446. PMID: 16152610Free PMC Article

Recent systematic reviews

Occult metastases of oral maxillary squamous cell carcinoma: Systematic review and meta-analysis.
de la Fuente C, Prat-Valero N, Alberola-Ferranti M, Mis-Castell D, Sáez-Barba M, Pujol-Pina R, Pamias-Romero J, Bescós-Atín C
Head Neck 2023 Mar;45(3):733-744. Epub 2022 Dec 14 doi: 10.1002/hed.27276. PMID: 36515647

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