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Metastatic malignant neoplasm in the lymph nodes

MedGen UID:
151947
Concept ID:
C0686619
Neoplastic Process
Synonyms: Lymph Node Metastases; Lymph Node Metastasis; Metastasis, Lymph Node
SNOMED CT: Secondary lymph node cancer (94392001); Secondary malignant neoplasm of lymph node (94392001); Metastatic malignant neoplasm to lymph node (94392001); Cancer metastatic to lymph nodes (94392001); Metastatic malignant neoplasm of lymph node (94392001)
 
Monarch Initiative: MONDO:0005438

Definition

The spread of a malignant neoplasm from its original site of growth to lymph nodes. [from NCI]

Professional guidelines

PubMed

Wright FC, Souter LH, Kellett S, Easson A, Murray C, Toye J, McCready D, Nessim C, Ghazarian D, Hong NJL, Johnson S, Goldstein DP, Petrella T; Melanoma Disease Site Group
Curr Oncol 2019 Aug;26(4):e541-e550. Epub 2019 Aug 1 doi: 10.3747/co.26.4885. PMID: 31548823Free PMC Article
Casali PG, Abecassis N, Aro HT, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, Buonadonna A, De Álava E, Dei Tos AP, Del Muro XG, Dileo P, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hassan B, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kasper B, Kopeckova K, Krákorová DA, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Sundby Hall K, Unk M, Van Coevorden F, van der Graaf WTA, Whelan J, Wardelmann E, Zaikova O, Blay JY; ESMO Guidelines Committee and EURACAN
Ann Oncol 2018 Oct 1;29(Suppl 4):iv51-iv67. doi: 10.1093/annonc/mdy096. PMID: 29846498
Li H, Wu X, Cheng X
J Gynecol Oncol 2016 Jul;27(4):e43. doi: 10.3802/jgo.2016.27.e43. PMID: 27171673Free PMC Article

Recent clinical studies

Etiology

Fu N, Fu W, Chen H, Chai W, Qian X, Wang W, Jiang Y, Shen B
Int J Surg 2023 Aug 1;109(8):2196-2203. doi: 10.1097/JS9.0000000000000469. PMID: 37216230Free PMC Article
Betancourt-Cuellar SL, Benveniste MFK, Palacio DP, Hofstetter WL
Radiol Clin North Am 2021 Mar;59(2):219-229. doi: 10.1016/j.rcl.2020.11.008. PMID: 33551083
Wang B, Zhang Y, Qing T, Xing K, Li J, Zhen T, Zhu S, Zhan X
Sci Rep 2021 Jan 13;11(1):1141. doi: 10.1038/s41598-020-80881-2. PMID: 33441952Free PMC Article
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Shum JW, Dierks EJ
Oral Maxillofac Surg Clin North Am 2014 May;26(2):209-21. Epub 2014 Mar 20 doi: 10.1016/j.coms.2014.01.007. PMID: 24656885

Diagnosis

Adler C, Lubner MG, Menias CO, Lubner SJ, Dahiya N
Abdom Radiol (NY) 2022 Jun;47(6):2244-2253. Epub 2022 Mar 22 doi: 10.1007/s00261-022-03487-4. PMID: 35316379
Wuthrick EJ, Harrison LB
Semin Radiat Oncol 2019 Apr;29(2):91-92. doi: 10.1016/j.semradonc.2018.11.009. PMID: 30827457
Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB
Eur Urol 2018 Apr;73(4):560-569. Epub 2018 Jan 9 doi: 10.1016/j.eururo.2017.12.018. PMID: 29325693
Das D, Gupta M, Kaur H, Kalucha A
J Oral Sci 2011 Jun;53(2):137-41. doi: 10.2334/josnusd.53.137. PMID: 21712616
Tait CR, Dodwell D, Horgan K
J Pathol 2004 May;203(1):515-8. doi: 10.1002/path.1544. PMID: 15095473

Therapy

Faries MB
J Surg Oncol 2022 Jan;125(1):34-37. doi: 10.1002/jso.26744. PMID: 34897707
Mejia JC, Pasko J
Surg Clin North Am 2020 Jun;100(3):535-549. Epub 2020 Apr 16 doi: 10.1016/j.suc.2020.02.013. PMID: 32402299
Euhus DM
Breast J 2020 Jan;26(1):35-38. Epub 2019 Dec 26 doi: 10.1111/tbj.13719. PMID: 31876073
Diab Y
Int J Gynecol Cancer 2017 Jan;27(1):154-158. doi: 10.1097/IGC.0000000000000853. PMID: 27792042Free PMC Article
Bartella L, Smith CS, Dershaw DD, Liberman L
Radiol Clin North Am 2007 Jan;45(1):45-67. doi: 10.1016/j.rcl.2006.10.007. PMID: 17157623

Prognosis

Yokoyama S, Watanabe T, Fujita Y, Matsumura S, Ueda K, Nagano S, Kinoshita I, Murakami D, Tabata H, Tsuji T, Ozawa S, Tamaki T, Nakatani Y, Oka M
PLoS One 2023;18(4):e0284536. Epub 2023 Apr 13 doi: 10.1371/journal.pone.0284536. PMID: 37053292Free PMC Article
Li J, Zhang X, Xu X, Zhao Q, Yang Q, He M, Chen X, Zhao J
Dis Markers 2022;2022:5615009. Epub 2022 Sep 30 doi: 10.1155/2022/5615009. PMID: 36246556Free PMC Article
Teichgraeber DC, Perez F, Guirguis MS, Kapoor MM, Whitman GJ
Ultrasound Q 2021 Jan 13;37(1):43-51. doi: 10.1097/RUQ.0000000000000546. PMID: 33464028
Rao VU, Patil PH, Rajaram BV
J Cancer Res Ther 2016 Jul-Sep;12(3):1114-1116. doi: 10.4103/0973-1482.164705. PMID: 28054520
Das D, Gupta M, Kaur H, Kalucha A
J Oral Sci 2011 Jun;53(2):137-41. doi: 10.2334/josnusd.53.137. PMID: 21712616

Clinical prediction guides

Alameer E, Eagan A, Scholfield DW, Woods RSR, Tuttle RM, Wong RJ, Patel SG, Ganly I
JAMA Otolaryngol Head Neck Surg 2024 Jan 1;150(1):49-56. doi: 10.1001/jamaoto.2023.3668. PMID: 37971746Free PMC Article
Kim DH, Kim SW, Hwang SH
Laryngoscope 2021 Sep;131(9):1990-1996. Epub 2021 Jan 25 doi: 10.1002/lary.29426. PMID: 33493364
O'Rourke C, Welaratne I, Cournane S, McLoughlin LC, Reynolds JV, Johnston C, Sheehy N
Eur J Radiol 2020 Apr;125:108860. Epub 2020 Feb 11 doi: 10.1016/j.ejrad.2020.108860. PMID: 32065926
Thoeny HC, De Keyzer F, King AD
Radiology 2012 Apr;263(1):19-32. doi: 10.1148/radiol.11101821. PMID: 22438440
Edge SB, Compton CC
Ann Surg Oncol 2010 Jun;17(6):1471-4. doi: 10.1245/s10434-010-0985-4. PMID: 20180029

Recent systematic reviews

Wei X, Wang X, Xiong J, Li C, Liao Y, Zhu Y, Mao J
Biomed Res Int 2022;2022:9959649. Epub 2022 May 18 doi: 10.1155/2022/9959649. PMID: 35647194Free PMC Article
Akazawa M, Hashimoto K
Artif Intell Med 2021 Oct;120:102164. Epub 2021 Sep 3 doi: 10.1016/j.artmed.2021.102164. PMID: 34629152
Bedrikovetski S, Dudi-Venkata NN, Kroon HM, Seow W, Vather R, Carneiro G, Moore JW, Sammour T
BMC Cancer 2021 Sep 26;21(1):1058. doi: 10.1186/s12885-021-08773-w. PMID: 34565338Free PMC Article
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Chang JM, Leung JWT, Moy L, Ha SM, Moon WK
Radiology 2020 Jun;295(3):500-515. Epub 2020 Apr 21 doi: 10.1148/radiol.2020192534. PMID: 32315268

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